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Antibody Drug Conjugates (ADCs)

With more than 30 years of experience in bioconjugation, SAFC has become a leading expert for the conjugation of highly active molecules

Targeted Delivery Through Conjugation

Antibody-drug conjugation technology uses monoclonal antibodies or other biologics to deliver highly active or potent pharmaceutical ingredients (HPAPIs) to targeted cells. In conjugated form, the HPAPIs exhibits more selective therapeutic activity, sparing non-target cells from many of the toxic effects and improving the safety profile. Customers are quickly adapting these complex technologies and employing them to develop new oncology products that are more targeted and safer.

Comprehensive ADC Solutions

SAFC & Baxter’s BioPharma Solutions business (BPS), two of the leading contract manufacturing organizations in the ADC space, are now offering a combined approach for your antibody-drug conjugate to simplify the supply chain and provide comprehensive, coordinated and collaborative services for the development, manufacturing, and testing of bulk drug substance and drug product. Together we offer a full range of services needed for ADCs:

  • Conjugation
  • mAbs, linkers and payloads
  • Process development
  • Technology transfer
  • Analytical method development and validation
  • Stability studies for bulk drug substance and drug product
  • Formulation development
  • Fill/finish including lyophilization


Simplifying the Pathway to Patients

SAFC’s ADC Contract Manufacturing footprint offers comprehensive solutions for your Antibody-Drug Conjugate.

ADC Capabilities
From preclinical to commercial, SAFC has dedicated assets and the expertise needed for development, manufacturing and testing of your ADC.

HPAPIs and Linkers
SAFC has over 25 years of experience
working with highly potent compounds
from grams to more than 100 kg
batches at our Madison (US) facilities.

Formulation & Fill/Finish
Our combined approach with Baxter's
BioPharma Solutions offers comprehensive, coordinated and collaborative services for the development, manufacturing, and testing of BDS and DP.
GMP mAb Production
With Provantage® biodevelopment services, you benefit from state-of-the-art GMP production.