CellASIC® ONIX Microfluidic System

 November 2019

 

Consequences of dosing and timing on the antibacterial effects of ADEP antibiotics
International Journal of Medical Microbiology, Volume 309, Issue 7, November 2019, Article 151329
Christian Mayer, Peter Sass, Heike Brötz-Oesterhelt
Metabolic interaction of hydrogen peroxide and hypoxia in zebrafish fibroblasts
Free Radical Biology and Medicine, In press, journal pre-proof, Available online 15 November 2019
Valentina Dikova, Julia Vorhauser, Anne Geng, Bernd Pelster, Adolf Michael Sandbichler
Decoupling of Rates of Protein Synthesis from Cell Expansion Leads to Supergrowth
Cell Systems, Volume 9, Issue 5, 27 November 2019, Pages 434-445.e6
Benjamin D. Knapp, Pascal Odermatt, Enrique R. Rojas, Wenpeng Cheng, Fred Chang

 

 October 2019

Decoupling of Rates of Protein Synthesis from Cell Expansion Leads to Supergrowth
Cell Systems, In press, corrected proof, Available online 6 November 2019
Benjamin D. Knapp, Pascal Odermatt, Enrique R. Rojas, Wenpeng Cheng, Fred Chang

 

 September 2019

Effects of intrinsic microbial stress factors on viability and physiological condition of yeasts isolated from spontaneously fermented cereal doughs
International Journal of Food Microbiology, Volume 304, 2 September 2019, Pages 75-88
Marcel Houngbédji, Pernille Johansen, S. Wilfrid Padonou, D. Joseph Hounhouigan, Lene Jespersen

 

 August 2019

Effects of intrinsic microbial stress factors on viability and physiological condition of yeasts isolated from spontaneously fermented cereal doughs
Research article
International Journal of Food Microbiology, Volume 304, 2 September 2019, Pages 75-88
Marcel Houngbédji, Pernille Johansen, S. Wilfrid Padonou, D. Joseph Hounhouigan, Lene Jespersen

 

 July 2019

Consequences of dosing and timing on the antibacterial effects of ADEP antibiotics
Research article
International Journal of Medical Microbiology, Page 151329, In Press, Corrected Proof, Available online 14 July 2019
Christian Mayer, Peter Sass, Heike Brötz-Oesterhelt

 

 June 2019

Condensin-Mediated Chromosome Folding and Internal Telomeres Drive Dicentric Severing by Cytokinesis
Research article Molecular Cell, In Press, Corrected Proof, Available online 13 June 2019
Thomas M. Guérin, Claire Béneut, Natalja Barinova, ... Stéphane Marcand

 

 May 2019

Effects of intrinsic microbial stress factors on viability and physiological condition of yeasts isolated from spontaneously fermented cereal doughs
Research article
International Journal of Food Microbiology, Volume 304, Pages 75-88,
Marcel Houngbédji, Pernille Johansen, S. Wilfrid Padonou, ... Lene Jespersen

 

 April 2019

Reductional Meiosis I Chromosome Segregation Is Established by Coordination of Key Meiotic Kinases
Research article
Developmental Cell, In press, corrected proof, Available online 25 April 2019
Stefan Galander, Rachael E. Barton, Weronika E. Borek, Christos Spanos, Adèle L. Marston
Keywords: Meiosis, Chromosome segregation, Cohesin, Polo kinase, Kinetochore, Spo13, Monoorientation, Shugoshin, Hrr25, DDK
Magnesium Flux Modulates Ribosomes to Increase Bacterial Survival
Research article
Cell, Volume 177, Issue 2, 4 April 2019, Pages 352-360.e13
Dong-yeon D. Lee, Leticia Galera-Laporta, Maja Bialecka-Fornal, Eun Chae Moon, Gürol M. Süel
Keywords: Membrane potential, Single-cell dynamics, Ion flux, Magnesium, Cations, Ion transporters, Ribosomes, Antibiotics, Bacterial survival

 

 March 2019

Magnesium Flux Modulates Ribosomes to Increase Bacterial Survival
Research Article
Cell, Volume 177, Issue 2, 4 April 2019, Pages 352-360.e13
Dong-yeon D. Lee, Leticia Galera-Laporta, Maja Bialecka-Fornal, Eun Chae Moon, Gürol M. SüelKeywords:  Membrane potential, Single-cell dynamics, Ion flux, Magnesium, Cations, Ion transporters, Ribosomes, Antibiotics, Bacterial survival

 

 February 2019

The DNA Damage Checkpoint and the Spindle Position Checkpoint Maintain Meiotic Commitment in Saccharomyces cerevisiae
Research article
Current Biology, Volume 29, Issue 3, 4 February 2019, Pages 449-460.e2
Olivia Ballew, Soni Lacefield
Keywords: Saccharomycetales, Cytokinesis, Mitotic exit

 

 January 2019

A Surface-Induced Asymmetric Program Promotes Tissue Colonization by Pseudomonas aeruginosa
Research article
Cell Host & Microbe, Volume 25, Issue 1, 9 January 2019, Pages 140-152.e6
Benoît-Joseph Laventie, Matteo Sangermani, Fabienne Estermann, Pablo Manfredi, Urs Jenal
Keywords: surface sensing; flagella; type IV pili; c-di-GMP; second messenger; asymmetric division; tissue colonization; Pseudomonas aeruginosa; virulence

 

 December 2018

 

Using time-lapse fluorescence microscopy to study gene regulation
Review article
Methods, In Press, Corrected Proof, Available online 29 December 2018 Fan Zou, Lu Bai

 

 November 2018

 

Bifunctional Immunity Proteins Protect Bacteria against FtsZ-Targeting ADP-Ribosylating Toxins
Cell, Volume 175, Issue 5, 15 November 2018, Pages 1380-1392.e14 See-Yeun Ting, Dustin E. Bosch, Sarah M. Mangiameli, Matthew C. Radey, Joseph D. Mougous

 

 October 2018

 

The p38α Stress Kinase Suppresses Aneuploidy Tolerance by Inhibiting Hif-1α Cell Reports
Volume 25, Issue 3, 16 October 2018, Pages 749-760.e6 Susana Simões-Sousa, Samantha Littler, Sarah L. Thompson, Paul Minshall, Stephen S. Taylor
Bifunctional Immunity Proteins Protect Bacteria against FtsZ-Targeting ADP-Ribosylating Toxins Cell
In press, corrected proof, Available online 18 October 2018 See-Yeun Ting, Dustin E. Bosch, Sarah M. Mangiameli, Matthew C. Radey, Joseph D. Mougous

 

 September 2018

 

Soluble antigen arrays disarm antigen-specific B cells to promote lasting immune tolerance in experimental autoimmune encephalomyelitis
Journal of Autoimmunity, Volume 93, September 2018, Pages 76-88
Brittany L. Hartwell, Chad J. Pickens, Martin Leon, Laura Northrup, … Cory Berkland
Integration of Multiple Metabolic Signals Determines Cell Fate Prior to Commitment
Molecular Cell, Volume 71, Issue 5, 6 September 2018, Pages 733-744.e11

Orlando Argüello-Miranda, Yanjie Liu, N. Ezgi Wood, Piya Kositangool, Andreas Doncic
Interdependence between EGFR and Phosphatases Spatially Established by Vesicular Dynamics Generates a Growth Factor Sensing and Responding Network
Cell Systems, Volume 7, Issue 3, 26 September 2018, Pages 295-309.e11
Angel Stanoev, Amit Mhamane, Klaus C. Schuermann, Hernán E. Grecco, … Philippe I. H. Bastiaens

 

 August 2018

 

Signal Percolation within a Bacterial Community
Original Research Article
Cell Systems, Available online 25 July 2018, Pages
Joseph W. Larkin, Xiaoling Zhai, Kaito Kikuchi, Samuel E. Redford, Arthur Prindle, Jintao Liu, Sacha Greenfield, Aleksandra M. Walczak, Jordi Garcia-Ojalvo, Andrew Mugler, Gürol M. Süel

 

 July 2018

 

Soluble antigen arrays disarm antigen-specific B cells to promote lasting immune tolerance in experimental autoimmune encephalomyelitis   
Original Research Article
Journal of Autoimmunity, Available online 12 July 2018, Pages
Brittany L. Hartwell, Chad J. Pickens, Martin Leon, Laura Northrup, Matthew A. Christopher, J. Daniel Griffin, Francisco Martinez-Becerra, Cory Berkland
Quantifying Nucleation In Vivo Reveals the Physical Basis of Prion-like Phase Behavior   
Original Research Article
Molecular Cell, Volume 71, Issue 1, 5 July 2018, Pages 155-168.e7
Tarique Khan, Tejbir S. Kandola, Jianzheng Wu, Shriram Venkatesan, Ellen Ketter, Jeffrey J. Lange, Alejandro Rodríguez Gama, Andrew Box, Jay R. Unruh, Malcolm Cook, Randal Halfmann

Graphical Abstract

 

 June 2018

 

Nascent teichoic acids insertion into the cell wall directs the localization and activity of the major pneumococcal autolysin LytA   
Original Research Article
The Cell Surface, Available online 12 June 2018, Pages
J. Bonnet, C. Durmort, I. Mortier-Barrière, N. Campo, M. Jacq, C. Moriscot, D. Straume, K.H. Berg, L. Håvarstein, Y-S. Wong, T. Vernet, A.M. Di Guilmi

Graphical abstract

Recent advances in microfluidic technology for manipulation and analysis of biological cells (2007–2017)   
Review Article
Analytica Chimica Acta, Available online 26 June 2018, Pages
Md Kowsar Alam, Koomson Emmanuel, Zou Heng, Yi Changqing, Li Cheuk-Wing, Xu Tao, Yang Mengsu

Graphical abstract

Image 1

 

 May 2018

 

Phosphorylation-Mediated Clearance of Amyloid-like Assemblies in Meiosis
Original Research Article
Developmental Cell, Volume 45, Issue 3, 7 May 2018, Pages 392-405.e6
Kayla Carpenter, Rachel Brietta Bell, Julius Yunus, Angelika Amon, Luke Edwin Berchowitz

Graphical Abstract

G1/S Transcription Factor Copy Number Is a Growth-Dependent Determinant of Cell Cycle Commitment in Yeast
Original Research Article
Cell Systems, Volume 6, Issue 5, 23 May 2018, Pages 539-554.e11
Savanna Dorsey, Sylvain Tollis, Jing Cheng, Labe Black, Stephen Notley, Mike Tyers, Catherine A. Royer

Graphical Abstract

 

 April 2018

 

MreB filaments align along greatest principal membrane curvature to orientcell wall synthesis.
Elife. 2018 Feb 22;7. pii: e32471. doi: 10.7554/eLife.32471.
Hussain S, Wivagg CN, Szwedziak P, Wong F, Schaefer K, Izoré T, Renner LD, Holmes MJ, Sun Y, Bisson-Filho AW, Walker S, Amir A, Löwe J, Garner EC.
Phase separation of a yeast prion protein promotes cellular fitness.
Science. 2018 Jan 5;359(6371). pii: eaao5654. doi: 10.1126/science.aao5654.
Franzmann TM, Jahnel M, Pozniakovsky A, Mahamid J, Holehouse AS, Nüske E, Richter D, Baumeister W, Grill SW, Pappu RV, Hyman AA, Alberti S.
A regulatory circuit of two lncRNAs and a master regulator directs cell fatein yeast.
Nat Commun. 2018 Feb 22;9(1):780. doi: 10.1038/s41467-018-03213-z.
Moretto F, Wood NE, Kelly G, Doncic A, van Werven FJ.
Spatial cues and not spindle pole maturation drive the asymmetry of astral microtubules between new and preexisting spindle poles
Molecular Biology of the CellVol. 29, No. 1, Articles, Published Online:23 Mar 2018
Jette Lengefeld , Eric Yen, Xiuzhen Chen, Allen Leary, Jackie Vogel, and Yves Barral
Roles of G1 cyclins in the temporal organization of yeast cell 2 cycle - a transcriptome-wide analysis
First posted online Mar. 23, 2018; doi: 10.1101/287573

Lotte Teufel, Katja Tummler, Max Flöttmann, Andreas Herrmann, Naama Barkai, Edda Klipp
Quantifying nucleation in vivo reveals the physical basis of prion-like phase behavior
doi: https://doi.org/10.1101/205690
Tarique Khan, Tejbir S. Kandola, Jianzheng Wu, Shriram Venkatesan, Ellen Ketter, Jeffrey J. Lange, Alejandro Rodríguez Gama, Andrew Box, Jay R. Unruh, Malcolm Cook, and Randal Halfmann
DISARM is a widespread bacterial defence system with broad anti phage activities.
Nat Microbiol. 2018 Jan;3(1):90-98. doi: 10.1038/s41564-017-0051-0. Epub 2017 Oct 30.
Ofir G, Melamed S, Sberro H, Mukamel Z, Silverman S, Yaakov G, Doron S, Sorek R.

 

 March 2018

 

Synthetic gene regulation for independent external induction of the Saccharomyces cerevisiaepseudohyphal growth phenotype
Georgios Pothoulakis & Tom Ellis
Single cell polarity in liquid phase facilitates tumour metastasis.
Nat Commun. 2018 Feb 28;9(1):887. doi: 10.1038/s41467-018-03139-6.
Lorentzen A1,2, Becker PF3, Kosla J3,4,5, Saini M6,7, Weidele K8, Ronchi P9, Klein C7, Wolf MJ10, Geist F6,7, Seubert B3,5, Ringelhan M3,11, Mihic-Probst D10, Esser K3, Roblek M12, Kuehne F3, Bianco G3, O'Connor T3,5, Müller Q11, Schuck K11, Lange S11, Hartmann D13, Spaich S14, Groß O15, Utikal J16,17, Haferkamp S18, Sprick MR6,7,19, Damle-Vartak A20, Hapfelmeier A21, Hüser N13, Protzer U3, Trumpp A6,7,19, Saur D11,19, Vartak N20, Klein CA8,22, Polzer B8, Borsig L12, Heikenwalder M23,24.
The SS18-SSX Oncoprotein Hijacks KDM2B-PRC1.1 to Drive Synovial Sarcoma
Original Research Article
Cancer Cell, Available online 1 March 2018, Pages
Ana Banito, Xiang Li, Aimée N. Laporte, Jae-Seok Roe, Francisco Sanchez-Vega, Chun-Hao Huang, Amanda R. Dancsok, Katerina Hatzi, Chi-Chao Chen, Darjus F. Tschaharganeh, Rohit Chandwani, Nilgun Tasdemir, Kevin B. Jones, Mario R.
Lineage space and the propensity of bacterial cells to undergo growth transitions
Arnab Bandyopadhyay, Christian Ray
Bistable emergence of oscillations in structured cell populations
Jintao Liu, Gurol Suel,  View ORCID Profile
Jordi Garcia-Ojalvo

 

 December 2017

 

Liver ‘organ on a chip’
Review Article
Experimental Cell Research, Available online 29 December 2017, Pages

Colin H Beckwitt, Amanda M Clark, Sarah Wheeler, D. Lansing Taylor, Donna B. Stolz, Linda Griffith, Alan Wells
Cells Escape an Operational Mitotic Checkpoint through a Stochastic Process
Original Research Article
Current Biology, Available online 14 December 2017, Pages
Paolo Bonaiuti, Elena Chiroli, Fridolin Gross, Andrea Corno, Claudio Vernieri, Martin Štefl, Marco Cosentino Lagomarsino, Michael Knop, Andrea Ciliberto
Homeostatic Cell Growth Is Accomplished Mechanically through Membrane Tension Inhibition of Cell-Wall Synthesis
Original Research Article
Cell Systems, Available online 1 December 2017, Pages
Enrique R. Rojas, Kerwyn Casey Huang, Julie A. Theriot

Graphical Abstract

 

 
October 2017
Polysaccharide matrices used in 3D in vitro cell culture systems
Review article, Biomaterials, Volume 141, October 2017, Pages 96-115
 
September 2017
The Adder Phenomenon Emerges from Independent Control of Pre- and Post-Start Phases of the Budding Yeast Cell Cycle Original research article, Current Biology, Volume 27, Issue 18, 25 September 2017, Pages 2774-2783.e3
 
August 2017
Clathrin-Independent Endocytosis Suppresses Cancer Cell Blebbing and Invasion
Open access, Original research article, Cell Reports, Volume 20, Issue 8, 22 August 2017, Pages 1893-1905
 
July 2017
Disruption of drug-resistant biofilms using de novo designed short α-helical antimicrobial peptides with idealized facial amphiphilicity
Open access, Original research article, Acta Biomaterialia, Volume 57, 15 July 2017, Pages 103-114
 
June 2017
Multivalent Soluble Antigen Arrays Exhibit High Avidity Binding and Modulation of B Cell Receptor-Mediated Signaling to Drive Efficacy against Experimental Autoimmune Encephalomyelitis.
Biomacromolecules. 2017 Jun 12;18(6):1893-1907. doi:10.1021/acs.biomac.7b00335. Epub 2017 May 17.
 
April 2017
Noisy Response to Antibiotic Stress Predicts Subsequent Single-Cell Survival in an Acidic Environment
Open access, Original research article, Cell Systems, Volume 4, Issue 4, 26 April 2017, Pages 393-403.e5
 
March 2017
Unconventional Targeting of a Thiol Peroxidase to the Mitochondrial Intermembrane Space Facilitates Oxidative Protein Folding
Open access, Original research article, Cell Reports, Volume 18, Issue 11, 14 March 2017, Pages 2729-2741
 
January 2017
Species-Independent Attraction to Biofilms through Electrical Signaling
Original research article, Cell, Volume 168, Issues 1–2, 12 January 2017, Pages 200-209.e12
 
September 2016
Cooperation of the ER-shaping proteins atlastin, lunapark, and reticulons to generate a tubular membrane network. Elife. 2016 Sep 13;5. pii: e18605. doi: 10.7554/eLife.18605.
Exploring Quantitative Yeast Phenomics with Single-Cell Analysis of DNA Damage Foci
Open archive, Original research article, Cell Systems, Volume 3, Issue 3, 28 September 2016, Pages 264-277.e10
 
August 2016
Switch-like Transitions Insulate Network Motifs to Modularize Biological Networks
Open access, Original research article, Cell Systems, Volume 3, Issue 2, 24 August 2016, Pages 121-132
 
June 2016
Relative Rates of Surface and Volume Synthesis Set Bacterial Cell Size
Open archive, Original research article, Cell, Volume 165, Issue 6, 2 June 2016, Pages 1479-1492
 
May 2016
The Yeast Cyclin-Dependent Kinase Routes Carbon Fluxes to Fuel Cell Cycle Progression
Open archive, Original research article, Molecular Cell, Volume 62, Issue 4, 19 May 2016, Pages 532-545
 
December 2015
Oligomerization but Not Membrane Bending Underlies the Function of Certain F-BAR Proteins in Cell Motility and Cytokinesis
Open archive, Original research article, Developmental Cell, Volume 35, Issue 6, 21 December 2015, Pages 725-736
 
November 2015
A Cellular System for Spatial Signal Decoding in Chemical Gradients
Open archive, Original research article, Developmental Cell, Volume 35, Issue 4, 23 November 2015, Pages 458-470
 
July 2015
Pathophysiologically relevant in vitro tumor models for drug screening
Review article, Drug Discovery Today, Volume 20, Issue 7, July 2015, Pages 848-855
 
June 2015
Glucose-Regulated Phosphorylation of the PUF Protein Puf3 Regulates the Translational Fate of Its Bound mRNAs and Association with RNA Granules
Open access, Original research article, Cell Reports, Volume 11, Issue 10, 16 June 2015, Pages 1638-1650
 
April 2015
A genetically encoded Förster resonance energy transfer sensor for monitoring in vivo trehalose-6-phosphate dynamics
Original research article, Analytical Biochemistry, Volume 474, 1 April 2015, Pages 1-7
 
March 2015
Classification of phenotypic subpopulations in isogenic bacterial cultures by triple promoter probing at single cell level
Original research article, Journal of Biotechnology, Volume 198, 20 March 2015, Pages 3-14
A Systematic Comparison of Mathematical Models for Inherent Measurement of Ciliary Length: How a Cell Can Measure Length and Volume Open archive, Original research article, Biophysical Journal, Volume 108, Issue 6, 24 March 2015, Pages 1361-1379
 
November 2014
Granules Harboring Translationally Active mRNAs Provide a Platform for P-Body Formation following Stress
Open access, Original research article, Cell Reports, Volume 9, Issue 3, 6 November 2014, Pages 944-954
 
September 2014
Engineering and evaluating drug delivery particles in microfluidic devices
Review article, Journal of Controlled Release, Volume 190, 28 September 2014, Pages 139-149
 
April 2014
Three-dimensional perfused cell culture
Review article, Biotechnology Advances, Volume 32, Issue 2, March–April 2014, Pages 243-254
 
August 2013
Loss of Cytochrome c Oxidase Promotes RAS-Dependent ROS Production from the ER Resident NADPH Oxidase, Yno1p, in Yeast
Open archive, Cell Metabolism, Volume 18, Issue 2, 6 August 2013, Pages 279-286
 
June 2013
Mechanical Consequences of Cell-Wall Turnover in the Elongation of a Gram-Positive Bacterium
Open archive, Original research article, Biophysical Journal, Volume 104, Issue 11, 4 June 2013, Pages 2342-2352
 
March 2013
Three-dimensional cell culture: the missing link in drug discovery
Review article, Drug Discovery Today, Volume 18, Issues 5–6, March 2013, Pages 240-249
Chapter 14: Microfluidic Hepatotoxicity Platform
Microfluidic Cell Culture Systems, 2013, Pages 341-355
 
November 2012
Organelle Size Equalization by a Constitutive Process
Open archive, Current Biology, Volume 22, Issue 22, 20 November 2012, Pages 2173-2179
 
September 2010
Space- and time-resolved protein dynamics in single bacterial cells observed on a chip
Original research article, Journal of Biotechnology, Volume 149, Issue 4, 15 September 2010, Pages 280-288