GC/MS/MS Analysis of Bisphenol A (BPA) in Canned Cream of Chicken Soup on the SLB-PAHms GC Column After SPME Using an Overcoated SPME Fiber

GC/MS/MS Analysis of Bisphenol A (BPA) in Canned Cream of Chicken Soup on the SLB-PAHms GC Column After SPME Using an Overcoated SPME Fiber

Conditions

Sample Prep Method
 

SPME fiber overcoated PDMS/DVB, 23 gauge
extraction immersion, 50 min, 50 °C, 250 rpm, vial penetration 34 mm
desorption process 3 min, 260°C
other sample prep information Sample was incubated prior to extraction for 10 min at 50°C, 400 rpm mixing.
Fiber was washed post-extraction and prior to desorption  in water for 0.5 min.
After desorption, fiber was post-baked at 270°C for 6 min.

Primary Analytical Method
 

instrument Agilent® 7890/7000C GC/MS/MS
column SLB-PAHms, 30 m x 0.25 mm I.D., 0.25 µm
oven 100 °C (3 min), 15 °C/min to 300 °C (10 min)
inj. temp. 260 °C
carrier gas helium, 1 mL/min constant flow
detector MS/MS
MSD interface 325 °C
scan range MRM:
BPA: 213/119, 213/91, 119/91
BPA-d16:  224/215, 224/97, 125/97
injection Splitless
liner 0.75 mm ID straight (for SPME)

Description

Analysis Note Use of bisphenol A (BPA)-based plastics in food and beverage containers continues to be a point of controversy. This study demonstrates the solid phase micro extraction (SPME) of BPA from canned cream of chicken soup using a PDMS overcoated PDMS/DVB fiber followed by GC/MS/MS analysis using SLB-PAHms GC Column. At a 10 ppb spiking level, accuracy of the SPME method  was 82% with a 9% difference in measurement values for replicate samples. 
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Thermogreen is a trademark of Sigma-Aldrich Co. LLC
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SLB is a trademark of Sigma-Aldrich Co. LLC
Application No. CLA020218A

Materials

     
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