)-(4-methylphenyl)sulfinyl]-1,1′-binapthaIene Diastereomers on Ascentis® Express C18

HPLC Analysis of 2,2′-Bis[(<I>S</I>)-(4-methylphenyl)sulfinyl]-1,1′-binapthaIene Diastereomers on Ascentis® Express C18


column Ascentis Express C18, 10 cm x 4.6 mm I.D., 2.7 µm particles (53827-U)
column temp. 35 °C
mobile phase [A] water; [B] methanol; (25:75, A:B)
flow rate 0.8 mL/min
pressure 2450 psi (169 bar)
sample (1R)-2,2′-Bis[(S )-(4-methylphenyl)sulfonyl]-1,1′-binapthalene, 25 μg/mL in methanol; (1S)-2,2′-Bis[(S)-(4-methylphenyl)sulfonyl]-1,1′-binapthalene, 50 μg/mL in methanol
injection 5 µL
detector UV, 240 nm


Analysis Note This application demonstrates the suitability of the Ascentis Express C18 for the separation of the diastereomers of by HPLC in reversed phase mode.
Categories Analytical Chromatography, Hydrocarbons
Featured Industry Chemicals and Industrial Polymers
Legal Information Ascentis is a registered trademark of Sigma-Aldrich Co. LLC
suitability application for HPLC


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