HPLC Analysis of Famotidine Tablets on Chromolith(R) HighResolution RP-18 endcapped 150 x 4.6mm

HPLC Analysis of Famotidine Tablets on Chromolith® HighResolution RP-18 endcapped 150 x 4.6mm

Conditions

sample preparation Dissolve 6.8 g of monobasic potassium phosphate in 750 mL of water. Adjust with 1 M potassium hydroxide to pH = 6.0 and dilute with water to 1 L.
column Chromolith HighResolution RP-18 endcapped, 150 x 4.6 mm (1.52023.0001)
column temp. 40 °C
mobile phase [A] 1 mL Triethylamine, adjust with glacial acetic acid to pH = 6.0, dilute with water to 1 L.; [B] acetonitrile; (93:7,:A:B)
flow rate 1.4 mL/min
pressure 696 psi (48 Bar)
sample System suitability solution
injection 50 μL
detector 275 nm cell: 11 μL

Description

Featured Industry Pharmaceutical (small molecule)
Legal Information Chromolith is a registered trademark of Merck KGaA, Darmstadt, Germany
suitability application for HPLC

Materials

     
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