TLC Analysis Of Paracetamol in Different Formulations on HPTLC Silica Gel 60 F254 MS-grade

TLC Analysis Of Paracetamol in Different Formulations on HPTLC Silica Gel 60 F254 MS-grade

Conditions

plate: 1.00934 HPTLC Silica gel 60 F254 MS-grade 20 cm x10 cm (1.00934.0001)
eluent: [A] aceton; [B] toluene; (1:1, A:B) containing 0.1% Acetic acid
migration distance: 5 cm
chamber: normal chamber without chamber saturation
detector: UV, 254 nm

Description

suitability application for TLC
Featured Industry Life Science and Biopharma
Analysis Note Sample prep: Suppository: One suppository containing 125 mg Paracetamol was diluted in
125 ml ethanol at 36°C and applied directly.
Pain syrup: 0.2 ml Paracetamol pain syrup containing 4 % Paracetamol was diluted in 7.8 ml methanol and applied directly.
Pill: One pill containing 500 mg Paracetamol was diluted in 500 ml methanol, filtered through a 0.45 μm Millex®-LCR syringe filter and applied directly.

Materials

     
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