Opioid CRM Kit for Accurate Fentanyl Testing

Opioid Certified Reference Material (CRM) Kits

The Centers for Disease Control and Prevention (CDC) has developed the Opioid Certified Reference Material (CRM) Kit to support laboratory detection of emerging opioids in the United States. The Opioid CRM Kit is now available from our Cerilliant® portfolio.

  • Addresses 99.8 percent of DEA fentanyl and fentanyl-related cases in the DEA 2019 Mid-Year Emerging Threat Report
  • Contains 1 milligram each of 22 opioids, including fentanyl analogs as well as their matched carbon-13 or nitrogen-15 isotopically-labeled internal standards
  • Supports detection of fentanyl, fentanyl-related compounds, and other related opioids

“We are excited to work with CDC in their mission to support detection of emerging opioids and fentanyl analogs,' said Aman Bhattacharjee, Head of Reference Materials franchise." The kit is designed to improve confirmation of analysis by mass spectrometry methods, an important assurance for accurate fentanyl testing.”

CDC Purchasing Cerilliant® Certified Reference Material Kits to Support Detection of Emerging Opioids

The kit is available free of charge to US laboratories. A requesting lab must have a current DEA registration for Schedules I and II controlled substances and comply with all respective state and local regulations.


Please visit cerilliant.com for instructions on how to request a free Opioid CRM Kit. CDC will review and approve all requests prior to shipment.

Accuracy, Precision, Consistency. Our high standards match yours.


The Opioid CRM Kit includes 1 mg/mL solutions of the following certified reference materials:

Acetyl fentanyl
Acetyl fentanyl-13C6
Acryl fentanyl HCl
Acryl fentanyl-13C6 HCl
4-ANPP -13C6
Benzylfentanyl HCl
Benzylfentanyl-13C6 HCl
Butyryl fentanyl
Butyryl fentanyl-13C6
Carfentanil Oxalate
Carfentanil-13C6 oxalate
Cyclopropyl fentanyl
Cyclopropyl fentanyl-13C6 HCl

para-Fluorobutyryl fentanyl (p-FBF)
para-Fluorobutyryl fentanyl-13C6
4-Fluoro fentanyl (4-FF)
4-Fluoro fentanyl-13C6
Furanyl fentanyl HCl (FU-F)
Furanyl fentanyl-13C6 HCl
(±)-beta-Hydroxythiofentanyl HCl
(±)-beta-Hydroxythiofentanyl-13C6 HCl
Methoxyacetyl fentanyl HCl
Methoxyacetyl fentanyl-13C6 HCl
4'-methyl acetyl fentanyl HCl
4'-methyl acetyl fentanyl-13C6 HCl
(±)-cis-3-Methylfentanyl HCl
3-Methylfentanyl-13C6 HCl

Norcarfentanil Oxalate
Norcarfentanil-13C6 oxalate
Norfentanyl oxalate
Norfentanyl-13C6 oxalate
Remifentanil-13C6 HCl
U-47700-13C2, 15N2
U-48800 HCl
U-48800-13C3, 15N2 HCl
Valeryl fentanyl HCl
Valeryl fentanyl-13C6 HCl