Supercritical Fluid Chromatography (SFC)

Supercritical fluid chromatography (SFC) is a chromatographic technique that uses a supercritical fluid such as carbon dioxide as the mobile phase. Typical applications are similar to normal phase HPLC, but with the benefit of not using high levels of organic solvents. Because it is easy to remove the mobile phase by simple evaporation, SFC is popular for preparative separations, especially chiral separations. We offer a broad range of SFC column chemistries for both chiral and achiral separations, from analytical to preparative scale.