Titration 4.0: SmartChemicals improve Titration Data Integrity & Efficiency

Bettina Straub-Jubb, Product Manager Titration

Titration goes digital

Titration goes digital - a joint project

In a joint project, METTLER TOLEDO, Switzerland, known as a manufacturer of high-end titration instruments, and Merck KGaA, Darmstadt, Germany, known as a producer of highest-quality analytical reagents and certified reference materials, have together developed this new titration technology to improve data integrity. With combined expert knowledge, we created a user-friendly and easy to use tool for transferring data wirelessly from the reagents to the titrator to open a new page of titration.

Introduction

This new technology using SmartChemicals in your titration process can secure your data transfer. Additionally, it saves time by eliminating manual data transmission.

Certificates of analysis often need to be downloaded and data subsequently copied manually to the titrator software for the correct calculation of the results and for documentation. This process is time consuming and creates sources of errors - such as typing mistakes.

The use of SmartChemicals eliminates these time- consuming steps and the potential for human errors by transferring all data wirelessly and instantly to the titrator software (see below). Volumetric solutions, Karl Fischer titrants and all standards are embedded with an RFID (Radio Frequency Identification) tag bearing all relevant information from the Certificate of Analysis.

Table 1 lists the information stored on the RFID tag for SmartTitrants and SmartStandards. Just a brief touch of the titrator’s SmartReader on the SmartChemical tag on the bottle (Figure 1) conveys all relevant data to the titrator software, saving time, reducing errors and ensuring maximum data integrity.

Secure data integrity in the titration process was never so easy

Secure data integrity in the titration process

RFID tag on the SmartChemical label contains all relevant data

All data needed for execution of the method, result calculation and documentation, such as product name, catalog number, lot/batch number, concentration/ purity, date of release, shelf life/expiry date, are stored on the RFID tag on the SmartChemical label (Figure 1) for seamless transfer to the titrator software. For standards, additional data is transferred, including molecular weight, supplier/producer name, uncertainty and compliance according to Pharmacopeias or ISO 17034 (Table 1).

Once the information is transferred from the RFID to the titrator, it is stored in the titration software and displayed on the touchscreen (Figure 2 & 3).

 

Figure 1. Titrator’s RFID reader and example label of a SmartChemical (RFID Tag marked).

Titrator’s RFID reader and example label

 

Table 1. RFID data content

Name Name
Concentration Concentration/Purity
Article number Article number
Lot/Batch no. Lot/Batch no.
Shelf life Expiry date
Initial opening date Initial opening date
Date of release (Date / Time) Date of release (Date / Time)
  Molecular weight
  Compliance
  Uncertainty

 

Figure 2. Information on SmartTitrant as displayed in the titrator software Figure 3. Information on SmartStandards as displayed in the titrator software
Information on SmartTitrant Information on SmartStandards

 

Previously opened chemicals are also recognized, and the initial opening date is stored on the RFID tag and is shown on the instrument’s touchscreen. Expired chemicals are automatically blocked from use preventing an incompliance of the measurement. In addition, user-specific guidelines regarding use period after opening can be set up and monitored by entering an individual life span into the software.

SmartChemicals are compatible with the METTLER TOLEDO instruments

Excellence Titrator models Compact Titrator models
Compact Titrator models G10S, G20S, V30S, V20S, V10S Excellence Titrator models T5, T7, T9

Conclusion

SmartChemicals with the RFID tag on the label provide

  • Secure data transfer – ensures complete and correct reagent data
  • Ease of use – intuitive operation and convenient data transfer in one touch
  • Extended quality management – titer determination, shelf life, compliance data, initial opening date
  • Improved efficiency – fast data transfer - saves time no manual writing and no need to employ the four-eyes principle

Supelco® SmartChemicals - product list

All products ending with a “3” as last digit, are embedded with an RFID tag

   To order contact us

 

Article No. Name  Packsize/Qty Packaging
Titripur® Volumetric Solutions    
1003261003 Titripur® Hydrochloric acid soltuion in 2-propanol 0.1 mol 1 L PE bottle
1090601003 Titripur® Hydrochloric acid 0.1 mol 1 L PE bottle
1055441003 Titripur® Potassium hydroxide solution  0.1 mol 1 L PE bottle
1091151003 Titripur® Potassium hydroxide solution in ethanol 0.1 mol 1 L Glass bottle
1091141003 Titripur® Potassium hydroxide solution in ethanol 0.5 mol 1 L Glass bottle
1093511003 Titripur® Potassium hydroxide solution in methanol 0.5 mol 1 L Glass bottle
1084311003 Titripur® Titriplex III Solution 0.1 mol 1 L PE bottle
1084311073 Titripur® Titriplex III Solution 0.1 mol (for North America only) 1 L PE bottle
1090651003 Titripur® Perchloric acid solution 0.1 mol 1 L Glass bottle
1090749013 Titripur® Sulfuric acid solution 0.05 mol 1 L PE bottle
1090811003 Titripur® Silver nitrate solution 0.1 mol 1 L PE bottle
1090991003 Titripur® Iodine solution 0.05 mol 1 L Glass bottle
1091371003 Titripur® Sodium hydroxide solution 1 mol 1 L PE bottle
1091374003 Titripur® Sodium hydroxide solution 1 mol 4 L PE bottle
1091379013 Titripur® Sodium hydroxide solution 1 mol 10  L PE bottle
1091391003 Titripur® Sodium hydroxide solution 0.25 mol 1 L PE bottle
1091411003 Titripur® Sodium hydroxide solution  0.1 mol 1 L PE bottle
1091414003 Titripur® Sodium hydroxide solution  0.1 mol 4 L PE bottle
1091471003 Titripur® Sodium thiosulfate solution 0.1 mol 1 L PE bottle
1091474003 Titripur® Sodium thiosulfate solution 0.1 mol 4 L PE bottle
1091479013 Titripur® Sodium thiosulfate solution 0.1 mol 10 L PE bottle
1091641003 Titripur® Hanus solution 0.1 mol;  for determination of iodine number 1 L Glass bottle
Certipur® Certified Volumetric Standards according to ISO 17034
1024000083 Certipur® Potassium hydrogen phthalate CRM 80 g Glass bottle
1024010063 Certipur® Benzoic acid CRM 60 g Glass bottle
1024020083 Certipur® Iron(II) ethylenediammonium sulfate CRM 80 g Glass bottle
1024030083 Certipur® Potassium dichromate CRM 80 g Glass bottle
1024080083 Certipur® TRIS(Hydroxymethyl)aminomethane CRM 80 g Glass bottle
1024090103 Certipur® Zinc CRM 100 g Glass bottle
Aquastar® Karl Fischer Titrants
1880011003 Aquastar® CombiTitrant 1  one component reagents 1 mg H2O/ml 1 L Glass bottle
1880011043 Aquastar® CombiTitrant 1  one component reagents 1 mg H2O/ml (for North America only) 1 L Glass bottle
1880021003 Aquastar® CombiTitrant 2  one component reagents 2 mg H2O/ml 1 L Glass bottle
1880021043 Aquastar® CombiTitrant 2  one component reagents 2 mg H2O/ml (for North America only) 1 L Glass bottle
1880051003 Aquastar® CombiTitrant 5  one component reagents 5 mg H2O/ml 1 L Glass bottle
1880061003 Aquastar® CombiTitrant 5 Keto  one component reagents 5 mg H2O/ml 1 L Glass bottle
1880101003 Aquastar® Titrant 5 two component reagents  5 mg H2O/ml 1 L Glass bottle
1880101043 Aquastar® Titrant 5 two component reagents  5 mg H2O/ml (for North America only) 1 L Glass bottle
Aquastar® Certified Water Standards according to ISO 17034
1880510013 Aquastar® Water standard 0.1 % 10 x 8 ml  Ampoules
1880510313 Aquastar® Water standard 0.1 % (for North America only) 10 x 8 ml  Ampoules
1880520013 Aquastar® Water standard 1 % 10 x 8 ml  Ampoules
1880550013 Aquastar® Oil standard (15 to 30 ppm water) 10 x 8 ml  Ampoules
Note: more products will follow 2019/2020