CellASIC® ONIX Microfluidic Platform – Dynamic live cell analysis for yeast

Track live yeast cells easily with live cell control provided by the CellASIC® ONIX Microfluidic Platform.

Innovative microfluidic chambers hold yeast cells in a single focal plane, allowing you to induce and follow cell events during high magnifcation viewing. Using intuitive software, you can program automated media, nutrient, or drug changes to the cell culture chamber, enabling time-lapse experiments never before possible.

 

 

Popular Applications of the CellASIC® ONIX platform:

  • Cell response to media change
  • Induction of cell cycle events
  • GFP-linked nuclear traffcking
  • Live cell analysis of mitosis
  • Starvation and recovery
  • Gene expression
  • Protein localization
  • Mitochondrial inheritance
  • Phase contrast, fluorescence, brightfeld, confocal, TIRF and DIC microscopy

Visit our website to review application data, watch live yeast cell videos and read testimonials—all the tools you need to drive your research forward! www.emdmillipore.com/cellasic

Key Publications Using the CellASIC® ONIX Microfluidic System

Feed-forward regulation ensures stability and rapid reversibility of a cellular state. Doncic A, Skotheim JM. Mol Cell. 50 (2013)

Mps1 and Ipl1/Aurora B act sequentially to correctly orient chromosomes on the meiotic spindle of budding yeast. Meyer R, Kim S, Obeso D, Straight P, Winey M, Dawson D. Science. 339 (2013)

A mammalian-like DNA damage response of fission yeast to nucleoside analogs. Sabatinos SA, Mastro TL, Green MD, Forsburg SL. Genetics, 193 (2013) An algorithm to automate yeast segmentation and tracking. Doncic, Andreas, et al. PLoS One. 8 (2013)

Mitochondrial network size scaling in budding yeast. Rafelski S et al. Science. 338 (2012) Continued DNA synthesis in replication checkpoint mutants leads to fork collapse. Sabatinos SA, Green MD, Forsburg SL. Mol Cell Biol. 32 (2012)

Bacterial virulence proteins as tools to rewire kinase pathways in yeast and immune cells. Wei P, Wong W, Park J, Corcoran E, Peisajovich S, Onuffer J, Weiss A, Lim W. Nature. 488 (2012)

Optical sensors for measuring dynamic changes of cytosolic metabolite levels in yeast. Bermejo C, Haerizadeh F, Takanaga H, Chermak D, Frommer W. Nat Protoc. 6 (2011)

     
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