Custom Peptide Library | PEPscreen® Peptides

Experience affordable and fast delivery of custom peptide libraries for target identification. The PEPscreen peptide library is configured in a convenient plate format, perfect for screening applications, epitope mapping and peptide microarray production.

Product Specifications

  • Sequence Length: 6 to 20 amino acids
  • Amount: 0.5-2 mg or 2-5 mg
  • Modifications: Comprehensive offering including phosphorylation, biotin, fluorescein, stable isotopes, etc.
  • Format: Supplied dry in a 96-well tube rack
  • Options: Normalization and aliquoting (stock and copy libraries)
  • Minimum library size of 24 peptides

Peptide Library Design

We offer complimentary peptide library design services for overlapping peptide fragment libraries, alanine scanning libraries, truncation libraries and positional scanning libraries. A peptide design tool for generating different types of peptide libraries is currently in development. To request a quote or help designing a custom peptide library, please complete the online form.

Overlapping Peptide Library – Overlapping peptide fragments to cover the full length of your protein of interest.

Alanine Scanning Library – Systematically substitute each amino acid position on your peptide sequences with alanine- the smallest of the naturally occurring amino acids that maintains it chirality. Alanine mutagenesis can be a powerful tool for probing the effect of individual amino acids side chain to protein function and properties.

Truncation Library – Systematically remove flanking amino acids to determine the minimum length required for optimum activity. Once the essential amino acid residues for protein activity are identified by alanine scanning, the direction of truncation can be selected around these residues, rather than removing residues from both ends of the peptide sequence.

Positional Scanning Library – Optimize the peptide lead sequence. A selected position on the lead peptide is replaced with different amino acid (natural or unnatural) to improve the peptide properties such as biological activity, enzyme stability and solubility. The substitution can be performed on a single or multiple positions on a peptide sequence. A peptide library constructed using positional scanning can be very informative in studying protein interfaces whether in epitope mapping or protein-protein interaction.

Need help with your design?