Stable Isotopes

By: Lisa Roth, ChemFiles Volume 11 Article 1

Lisa Roth, Ph.D.
Product Manager

Stable isotope containing compounds are used in a variety of applications including tracers in clinical studies,1 labeled amino acids for use in protein quantification2 and standards for metabolic research.3 Historically, the introduction of stable isotopes has been a difficult, time consuming and costly process requiring the specialized skill of a stable isotope chemist. The reagents below were designed to introduce stable isotopes using standard chemical procedures.

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  1. Brown, L. D.; Cheung, A.; Harwood, J. E. F.; Battaglia, F. C.; J. Nut. 2009, 139, 1649.
  2. Hanke, S.; Besir, H.; Oesterhelt, D.; Mann, M.; J. Proteome. Res. 2008, 7, 1118.
  3. Li, C.; Hill, R.W.; Jones, A. D.; J. Chrom. B 2010, 878, 1809.

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