Ritter Group - Professor Product Portal

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Professor Tobias Ritter

The Ritter lab currently focuses on fluorination chemistry for late-stage functionalization of complex natural and unnatural products.  PhenoFluor™ has been developed as a general reagent for the selective, predictable, direct deoxyfluorination of complex alcohols and phenols. The conceptual advantage of PhenoFluor™, beyond its better safety profile, is manifested in its chemoselectivity, which results in the ability to selectively and predictably introduce fluorine also into complex small molecules with several hydroxyl groups.

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Jean Raynaud, Jessica Y Wu, Tobias Ritter
Angewandte Chemie. International edition in English 2012-11-19
Ironing rubber: Iminopyridine-based FeCl(2) catalysts catalyze the polymerization of 1,3-dienes and provide stereoselective access to elastomers such as polyisoprenes, polymyrcenes, and polyfarnesenes. The choice of ligand determines the double-bond geometry in the polymer repeating unit, which can be varied from trans/cis >99:...Read More
Pingping Tang, Weike Wang, Tobias Ritter
Journal of the American Chemical Society 2011-08-03
An operationally simple ipso fluorination of phenols with a new deoxyfluorination reagent is presented.Read More