Functional, Stereochemically Pure Monomer for ROMP Polymerization

By: Joe Porwoll, Material Matters 2010, 5.1, 1.

Material Matters 2010, 5.1, 1.

Joe Porwoll, President
Aldrich Chemical Co., Inc.

Do you have a compound that you wish Sigma-Aldrich® could list to help materials research? If it is needed to accelerate your research, it matters—please send your suggestion to and we will be happy to give it careful consideration.

Professor Karen Wooley of Texas – A&M University kindly suggested that we offer the exo-5-Norbornene-carboxylic acid (Aldrich Prod. No. 718149) as a product in our catalog. This compound is a functional, stereochemically pure monomer used in ring opening metathesis polymerization (ROMP) synthesis of well-defined polymer materials. The pure exo- monomer shows faster reaction times,1 higher conversion ratios, and better control of ROMP synthesis2 compared to the racemic analog. The carboxylic acid serves as a versatile handle that can be used to prepare a variety of polymers (e.g., glycopolymers) for biomedical applications.3-5

back to top 




  1. Fu, Q.; Seery, T. A. P. Polym. Prepr. 2001, 41 (1), 341-342.
  2. Pollino, J. M.; Stubbs, L. P.; Weck, M. Macromolecules 2003, 36, 2230-2234.
  3. Gordon, E. J.; Gestwicki, J. E.; Strong, L. E.; Kiessling, L. L. Chem. Biol. 2000, 7, 9-16.
  4. Strong, L. E.; Kiessling, L. L. J. Am. Chem. Soc. 1999, 121, 6193-6196.
  5. Owen, R. M.; Gestwicki, J. E.; Young, T.; Kiessling, L. L. Org. Lett. 2002, 4, 2293-2296.

back to top 

Related Links