Attention:

As we update our core systems, key features of the website including ordering and real-time price and availability, may be unavailable from 8 PM CST on Friday evening, September 20th until 9 AM CST on Saturday morning, September 21st.

Please note that you will still have telephone and email access to our local offices during this period.

We apologize for any inconvenience this may cause.

Webinar: Knockout Screening with Sanger Arrayed Genome-Wide CRISPR Libraries

Here we present the first genome wide, arrayed guide RNA screening libraries for CRISPR-Cas9. These libraries have been designed to cover 17166 human and 20430 mouse genes. To test the efficiency, we selected gRNAs targeting genes from the GPI anchor protein pathway. We observed that over 95% of these gRNAs successfully induced DNA cleavage and consequently gene loss of function. These libraries offer the prospect for performing high-throughput screens for genes of considerable scientific and therapeutic value in mouse and human cells.