Biomedical Applications of Magnetic Micro- and Nanoparticles

Overview

The use of magnetic micro- and nanoparticles for biomedical applications was first proposed in the 1920s as a way to measure the rheological properties of the cytoplasm. Since that time, particle synthesis techniques and functionality have advanced significantly. Magnetic micro- and nanoparticles are now used in a variety of biomedical applications such as targeted drug delivery, MRI contrast enhancement, gene transfection, immunoassay and cell sorting. More recently, magnetic micro- and nanoparticles have been used to investigate and manipulate cellular processes both in vitro and in vivo.

Key Learning Objectives

  • Understanding of magnetic properties of materials
  • Introduction to applications in biomedicine that employ magnetic micro- and nanoparticles
  • Specific overview of magnetically actuated receptor signaling, gene transfection, and hyperthermia

Who Should Watch

  • Material Scientists
  • Biomedical Researchers
  • Translational Researchers
  • Chemical Engineers


Dr. Jon Dobson is a professor of Biomedical Engineering & Biomaterials at University of Florida. Dr. Dobson’s research focuses on biomedical applications of magnetic micro- and nanoparticles. His group has developed novel technologies for 1) magnetic targeting and remote activation of cell signaling pathways for cell engineering and stem cell therapy; 2) magnetic nanoparticle-based gene transfection delivery; and 3) magnetic targeting of modified cell carriers for cancer therapy and regenerative medicine. In addition, he has also led a multi-national research program developing novel imaging and characterization techniques to quantify, characterize and map iron compounds related to neurodegenerative diseases such as Alzheimer’s and Parkinson’s.