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05-588

Anti-HET/SAF-B Antibody, clone 6F7

clone 6F7, Upstate®, from mouse

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

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biological source

mouse

Quality Level

100

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

6F7, monoclonal

species reactivity

human

manufacturer/tradename

Upstate®

technique(s)

immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

isotype

IgG

NCBI accession no.

NM_002555

UniProt accession no.

Q15424

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... SAFB(6294)

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05-486MABS1990M07-453
Anti-HET/SAF-B Antibody, clone 6F7 clone 6F7, Upstate®, from mouse

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Anti-HET/SAF-B Antibody, clone 6F7

Anti-FADD Antibody, clone 1F7 clone 1F7, Upstate®, from mouse

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Anti-FADD Antibody, clone 1F7

Anti-RhoB Antibody, clone 7F7 clone 7F7, from mouse

Sigma-Aldrich

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Anti-RhoB Antibody, clone 7F7

Anti-B-Raf Antibody Upstate®, from rabbit

Sigma-Aldrich

07-453

Anti-B-Raf Antibody

clone

6F7, monoclonal

clone

1F7, monoclonal

clone

7F7, monoclonal

clone

polyclonal

species reactivity

human

species reactivity

mouse, human

species reactivity

rat, mouse, hamster, porcine, human, chicken, monkey, rabbit

species reactivity

human, rat, mouse

biological source

mouse

biological source

mouse

biological source

mouse

biological source

rabbit

antibody form

purified immunoglobulin

antibody form

purified antibody

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

UniProt accession no.

Q15424

UniProt accession no.

Q13158

UniProt accession no.

P62745

UniProt accession no.

P15056

Gene Information

human ... SAFB(6294)

Gene Information

human ... FADD(8772)
mouse ... Fadd(14082)

Gene Information

human ... RHOB(388)

Gene Information

human ... BRAF(673)
mouse ... Braf(109880)
rat ... Rasd1(64455)

General description

130kDa

Immunogen

Peptide corresponding to residues 345-357 of human HET/SAF-B

Application

Anti-HET/SAF-B Antibody, clone 6F7 is a high quality Mouse Monoclonal Antibody for the detection of HET/SAF-B & has been validated in IP, WB, ICC & IHC.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Transcription Factors

Biochem/physiol Actions

HET/SAF-B

Physical form

0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
Format: Purified
Protein G Chromatography

Preparation Note

2 years at -20°C

Analysis Note

routinely evaluated by immunoblot on whole cell extracts or RIPA lysates from MCF-7 cells

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Qimin Zhang et al.
American journal of cancer research, 7(4), 935-945 (2017-05-05)
Bladder cancer is one of the most prevalent cancers worldwide, and increasing research has focused on new technologies for early detection of bladder cancer. For example, proteomic techniques for biomarker discovery have been implemented for the detection and analysis of
S Oesterreich et al.
Molecular endocrinology (Baltimore, Md.), 14(3), 369-381 (2000-03-09)
The estrogen receptor (ER) is a ligand-dependent transcription factor that acts in a cell- and promoter-specific manner. Evidence suggests that the activity of the ER can be regulated by a number of other stimuli (e.g. growth factors) and that the
Caroline Rivers et al.
BMC biology, 13, 111-111 (2015-12-24)
SAFB1 is a RNA binding protein implicated in the regulation of multiple cellular processes such as the regulation of transcription, stress response, DNA repair and RNA processing. To gain further insight into SAFB1 function we used iCLIP and mapped its
E Werwein et al.
Cell death & disease, 4, e511-e511 (2013-03-02)
B-Myb is a highly conserved member of the Myb transcription factor family that has essential roles in cell-cycle progression. Recent work has suggested that B-Myb is also involved in the cellular DNA-damage response. Here, we have investigated the fate of
Steven M Townson et al.
The Journal of biological chemistry, 278(22), 20059-20068 (2003-03-28)
We have characterized previously the nuclear matrix protein/scaffold attachment factor (SAFB) as an estrogen receptor corepressor and as a potential tumor suppressor gene in breast cancer. A search of the human genome for other potential SAFB family members revealed that
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