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Merck

655205

TWEEN® 20

Non-ionic detergent

Synonym(s):

TWEEN® 20, Polysorbate 20, Polyoxyethylene (20) sorbitan monolaurate, PEG(20)sorbitan monolaurate, Polyethylene glycol sorbitan monolaurate, Polyoxyethylenesorbitan monolaurate

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
12161902
NACRES:
NA.25

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Product Name

TWEEN® 20, Non-ionic detergent used for immunoprecipitation and for the solubilization of membrane-bound proteins.

Quality Level

description

RTECS - TR7400000

form

liquid

mol wt

~1228

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

pale yellow

refractive index

n20/D 1.468 (lit.)

CMC

59 μM (HLB number 16.7)

solubility

water: 10%

density

1.095 g/mL at 25 °C (lit.)

shipped in

ambient

storage temp.

15-25°C

SMILES string

CCCCCCCCCCCC(=O)OCCOCC(C1C(C(CO1)OCCO)OCCO)OCCO

InChI

1S/C26H50O10/c1-2-3-4-5-6-7-8-9-10-11-24(30)34-19-18-31-20-22(32-15-12-27)26-25(35-17-14-29)23(21-36-26)33-16-13-28/h22-23,25-29H,2-21H2,1H3

InChI key

HMFKFHLTUCJZJO-UHFFFAOYSA-N

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Show Differences

1 of 4

This Item
P2287P7949P1379
form

liquid

form

viscous liquid

form

viscous liquid

form

viscous liquid

storage temp.

15-25°C

storage temp.

-

storage temp.

-

storage temp.

-

mol wt

~1228

mol wt

~1228

mol wt

~1228

mol wt

~1228

density

1.095 g/mL at 25 °C (lit.)

density

1.095 g/mL at 25 °C (lit.), 1.1 g/cm3 at 25 °C (lit.)

density

1.095 g/mL at 25 °C (lit.)

density

1.095 g/mL at 25 °C (lit.)

description

RTECS - TR7400000

description

non-ionic

description

non-ionic

description

non-ionic

Quality Level

100

Quality Level

300

Quality Level

300

Quality Level

300

General description

Non-ionic detergent used for immunoprecipitation and for the solubilization of membrane-bound proteins (CMC: 59 µM; HLB number: 16.7).

Application

Non-ionic detergent

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
TWEEN is a registered trademark of Croda International PLC

Disclaimer

Toxicity: Standard Handling (A)

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

527.0 °F - Pensky-Martens closed cup

Flash Point(C)

275 °C - Pensky-Martens closed cup


Certificates of Analysis (COA)

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Monika Wimmer et al.
Cell communication and signaling : CCS, 18(1), 61-61 (2020-04-12)
Cutaneous squamous cell carcinomas (cSCC) are the primary cause of premature deaths in patients suffering from the rare skin-fragility disorder recessive dystrophic epidermolysis bullosa (RDEB), which is in marked contrast to the rarely metastasizing nature of these carcinomas in the

Questions

  1. Hello! What is the concentration of this non-ionic detergent? Thank you!

    1 answer
    1. This product is considered a neat or pure liquid. The base molecular weight of this material is 1,228 daltons and the density is 1.095 g/mL. However, this is based on the assumption of 20 ethylene oxide units, 1 sorbitol, and 1 lauric acid. The critical micelle concentration of this detergent is 0.059 mM.

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