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Merck

MAB1955

Anti-Integrin α4 Antibody, clone P4C2

ascites fluid, clone P4C2, Chemicon®

Synonym(s):

CD49d

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702

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Product Name

Anti-Integrin α4 Antibody, clone P4C2, ascites fluid, clone P4C2, Chemicon®

biological source

mouse

conjugate

unconjugated

antibody form

ascites fluid

antibody product type

primary antibodies

clone

P4C2, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable
immunoprecipitation (IP): suitable

isotype

IgG3

NCBI accession no.

NM_000885.4

UniProt accession no.

P13612

shipped in

dry ice

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... ITGA4(3676)

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Anti-Integrin α4 Antibody, clone P4C2 ascites fluid, clone P4C2, Chemicon®

Sigma-Aldrich

MAB1955

Anti-Integrin α4 Antibody, clone P4C2

Anti-Integrin α4 Antibody, clone P1H4, azide free clone P1H4, Chemicon®, from mouse

Sigma-Aldrich

MAB16983Z

Anti-Integrin α4 Antibody, clone P1H4, azide free

Anti-Integrin α3 Antibody, clone ASC-1 (Azide Free) clone ASC-1, Chemicon®, from mouse

Sigma-Aldrich

MAB2056Z

Anti-Integrin α3 Antibody, clone ASC-1 (Azide Free)

Anti-Integrin α3 Antibody, clone ASC-1 clone ASC-1, Chemicon®, from mouse

Sigma-Aldrich

MAB2056

Anti-Integrin α3 Antibody, clone ASC-1

Gene Information

human ... ITGA4(3676)

Gene Information

human ... ITGA4(3676)

Gene Information

human ... ITGA3(3675)

Gene Information

human ... ITGA3(3675)

clone

P4C2, monoclonal

clone

P1H4, monoclonal

clone

ASC-1, monoclonal

clone

ASC-1, monoclonal

biological source

mouse

biological source

mouse

biological source

mouse

biological source

mouse

species reactivity

human

species reactivity

human, primate

species reactivity

human

species reactivity

human

antibody form

ascites fluid

antibody form

purified immunoglobulin

antibody form

culture supernatant

antibody form

purified antibody

UniProt accession no.

P13612

UniProt accession no.

P11215

UniProt accession no.

P26006

UniProt accession no.

P26006

Application

Research Category
Cell Structure
Research Sub Category
Integrins
This Anti-Integrin α4 Antibody, clone P4C2 is validated for use in IP, IH, FUNC for the detection of Integrin α4.
Immunofluorescence and immunoprecipitation.

Inhibits attachment of hematopoeitic cells and T-lymphocytes but not fibroblasts to fibronectin; typical titer is >1:1,000

Aggregation of Jurkat cells to 1:1600 dilution

Biochem/physiol Actions

alpha4 integrin. The alpha4beta1 integrin receptor recognizes an RGD-independent alternative adhesion site in the CS-1 region of fibronectin.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Other Notes

Replaces: 04-1131

Physical form

Liquid ascites containing sodium azide as a preservative.

Preparation Note

Store at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

12 - Non Combustible Liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Huanqing Gao et al.
Biochemical and biophysical research communications, 491(1), 204-208 (2017-07-18)
Adipogenesis is a process of differentiation from preadipocyte into adipocyte, and is regulated by several transcription factors, including the peroxisome proliferator-activated receptor gamma (PPARγ) and the CCAAT-enhancer-binding protein alpha (C/EBPα). CD36 is a membrane protein which contributes to the metabolic
Sonia A Cunningham et al.
The Journal of biological chemistry, 277(31), 27589-27592 (2002-06-19)
We have previously reported that junctional adhesion molecule 2 (JAM2) adheres to T cells through heterotypic interactions with JAM3. An examination of the cation dependence of JAM2 adhesion to HSB cells revealed a Mn(2+)-enhanced binding component indicative of integrin involvement.
L Koivisto et al.
Cell adhesion and communication, 7(3), 245-257 (2000-01-08)
Collaborative role of various fibronectin-binding integrins (alpha5beta1, alphavbeta1 and alphavbeta6) as mediators of cell adhesion and migration on fibronectin was studied using cultured HaCaT keratinocytes. This cell line spontaneously expressed all three fibronectin-binding integrins. In addition, the expression of alphavbeta6
Michelle B Chen et al.
Cancer research, 76(9), 2513-2524 (2016-03-19)
Tumor integrin β1 (ITGB1) contributes to primary tumor growth and metastasis, but its specific roles in extravasation have not yet been clearly elucidated. In this study, we engineered a three-dimensional microfluidic model of the human microvasculature to recapitulate the environment
Maria J Calzada et al.
The Journal of biological chemistry, 279(40), 41734-41743 (2004-08-05)
In addition to the three known beta(1) integrin recognition sites in the N-module of thrombospondin-1 (TSP1), we found that beta(1) integrins mediate cell adhesion to the type 1 and type 2 repeats. The type 1 repeats of TSP1 differ from
View All Related Papers

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