O7885

Okadaic acid potassium salt from Prorocentrum concavum

Name: Okadaic acid potassium salt from <I>Prorocentrum concavum</I>
Brand: SIGMA

≥90% (HPLC), powder

Synonym(s):

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About This Item

Empirical Formula (Hill Notation):

C₄₄H₆₇KO₁₃

CAS Number:

155751-72-7

Molecular Weight:

843.09

NACRES:

NA.77

PubChem Substance ID:

24898050

UNSPSC Code:

12352106

MDL number:

MFCD00214356

Key Documents

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Product Name

Okadaic acid potassium salt from Prorocentrum concavum, ≥90% (HPLC), powder

InChI

1S/C46H72O13.K/c1-27-20-35(56-46(22-27)36(48)12-15-42(7,59-46)24-43(8,52)40(50)51)28(2)10-14-41(6)17-18-45(58-41)16-11-34-39(57-45)37(49)30(4)38(55-34)33(47)21-29(3)32-23-44(26-54-31(32)5)13-9-19-53-25-44;/h10,14,22,28-29,31-39,47-49,52H,4,9,11-13,15-21,23-26H2,1-3,5-8H3,(H,50,51);/q;+1/p-1/b14-10+;

SMILES string

[K+].CC(CC(O)C1OC2CCC3(CCC(C)(O3)\C=C\C(C)C4CC(C)=CC5(O4)OC(C)(CCC5O)CC(C)(O)C([O-])=O)OC2C(O)C1=C)C6CC7(CCCOC7)COC6C

InChI key

CWKZDWKRECTBCU-KMZJGFRYSA-M

biological source

plant (Prorocentrum concavum)

assay

≥90% (HPLC)

form

powder

color

white

solubility

H₂O: 0.1 mg/mL
DMSO: soluble
ethanol: soluble

storage temp.

−20°C

Quality Level

200

Related Categories

Bioactive Small Molecule Inhibitors

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Show Differences

1 of 4

This Item	O8010	O7760	O9381
Sigma-Aldrich O7885 Okadaic acid potassium salt from Prorocentrum concavum	Sigma-Aldrich O8010 Okadaic acid ammonium salt from Prorocentrum concavum	Sigma-Aldrich O7760 Okadaic acid sodium salt from Prorocentrum concavum	Sigma-Aldrich O9381 Okadaic acid from Prorocentrum concavum
form powder	form solid	form film	form powder
assay ≥90% (HPLC)	assay ≥90% (HPLC)	assay ≥90% (HPLC)	assay 92-100% (HPLC)
Quality Level 200	Quality Level 200	Quality Level 200	Quality Level 200
storage temp. −20°C	storage temp. −20°C	storage temp. −20°C	storage temp. −20°C
solubility H₂O: 0.1 mg/mL, ethanol: soluble, DMSO: soluble	solubility H₂O: 0.1 mg/mL, DMSO: soluble, ethanol: soluble	solubility 0.1% acetic acid in CH₃CN: H₂O (1:1): 250 μg/mL, clear, colorless	solubility DMSO: ≥1 mg/mL, ethanol: ≥1 mg/mL, methanol: ≥1 mg/mL, H₂O: insoluble
color white	color white	color translucent	color -

Biochem/physiol Actions

Dinoflagellate toxin and an ionophore-like polyether derivative of a 38 carbon, fatty acid. Readily enters cells. Inhibitor of type 1 and type 2A protein phosphatases. Does not inhibit tyrosine phosphatases, alkaline phosphatases or acid phosphatase. Known tumor promotor. Used to study various cellular processes including cell cycle, apoptosis, nitric oxide metabolism and calcium signaling.

Okadaic acid is a dinoflagellate toxin and an ionophore-like polyether derivative of a 38 carbon, fatty acid.

pictograms

GHS06

signalword

Danger

hcodes

H301 + H311 + H331,H315

pcodes

P261 - P280 - P301 + P330 + P331 + P310 - P302 + P352 + P312 - P304 + P340 + P311 - P403 + P233

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Skin Irrit. 2

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

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