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Merck

1336500

USP

Imidazole

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

1,3-Diaza-2,4-cyclopentadiene, Glyoxaline

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200 MG

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About This Item

Empirical Formula (Hill Notation):
C3H4N2
CAS Number:
288-32-4
Molecular Weight:
68.08
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329750151
MDL number:
MFCD00005183
Beilstein/REAXYS Number:
103853

Key Documents

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Product Name

Imidazole, United States Pharmacopeia (USP) Reference Standard

InChI key

RAXXELZNTBOGNW-UHFFFAOYSA-N

SMILES string

c1c[nH]cn1

InChI

1S/C3H4N2/c1-2-5-3-4-1/h1-3H,(H,4,5)

grade

pharmaceutical primary standard

vapor pressure

<1 mmHg ( 20 °C)

API family

imidazole

manufacturer/tradename

USP

pKa (25 °C)

6.95

bp

256 °C (lit.)

mp

88-91 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

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PHR1180IX0005I5513
Imidazole United States Pharmacopeia (USP) Reference Standard

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1336500

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Imidazole Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1180

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Imidazole Meets ACS Specifications, Meets Reagent Specifications for testing USP/NF monographs GR ACS

Sigma-Aldrich

IX0005

Imidazole

Imidazole Molecular Biology, &#8805;99% (titration)

Sigma-Aldrich

I5513

Imidazole

manufacturer/tradename

USP

manufacturer/tradename

-

manufacturer/tradename

-

manufacturer/tradename

-

grade

pharmaceutical primary standard

grade

certified reference material, pharmaceutical secondary standard

grade

-

grade

for molecular biology

format

neat

format

neat

format

-

format

-

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

-

application(s)

diagnostic assay manufacturing
genomic analysis
life science and biopharma
microbiology

vapor pressure

<1 mmHg ( 20 °C)

vapor pressure

<1 mmHg ( 20 °C)

vapor pressure

0.003 hPa ( 20 °C)

vapor pressure

<1 mmHg ( 20 °C)

API family

imidazole

API family

imidazole

API family

-

API family

-

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Application

Excellent for buffers in the range of pH 6.2-7.8
Imidazole USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Clotrimazole
  • Clotrimazole Topical Solution
  • Perindopril Erbumine
  • Moexipril Hydrochloride
  • Clotrimazole Vaginal Inserts
  • Sildenafil Citrate
  • Clotrimazole Lozenges

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 1B - Skin Corr. 1C

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 2

flash_point_f

293.0 °F - closed cup

flash_point_c

145 °C - closed cup

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Perindopril Erbumine
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 46(4) (2023)
Clotrimazole Vaginal Inserts
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 40(5), 1123-1123 (2016)
Clotrimazole Topical Solution
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 40(3), 1122-1122 (2016)
Moexipril Hydrochloride
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 38(3), 2992-2992 (2020)
Joy Rathjen et al.
Reproduction, fertility, and development, 26(5), 703-716 (2013-06-14)
Human embryonic stem (ES) cells have been proposed as a renewable source of pluripotent cells that can be differentiated into various cell types for use in research, drug discovery and in the emerging area of regenerative medicine. Exploitation of this
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Protocols

Sildenafil Citrate USP Method Using HPTLC Plates for the Limit of Imidazole Test

In the present study we demonstrate compliance of silica gel 60 F254 HPTLC plates with USP requirements, and how HPTLC plates are suitable for the Sildenafil citrate-Limit of Imidazole test.

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