Merck

Membrane Chromatography

Our Natrix® chromatography membrane technology provides a new level of downstream productivity and versatility. The macroporous structure, combined with high functional group density, enables high load capacity and excellent impurity removal at ultra-fast flow rates. With great performance in a single-use and scalable format, our innovative Natrix® products improve process economics and facility utilization.


Natrix® Q strong anion exchange chromatography membrane for single-use biomolecule purification

Natrix® Q chromatography membrane

A high-capacity, high-throughput strong anion exchange membrane chromatography device designed for biomolecule purification, Natrix® Q chromatography membrane is a porous polyacrylamide hydrogel containing a high density of pendant quaternary ammonium (Q) binding groups directly polymerized within an inert, macroporous membrane scaffold. The interconnected pore structure and high functional group density enables fast flow rates with impressive throughput to extremely high loads while maintaining excellent impurity removal across a wide range of buffer conditions. Natrix® Q delivers improvements in productivity, flexibility, economic utility, and process robustness for any bioprocess design.


RELATED PRODUCT RESOURCES






Highlights

Webinar: High Productivity Membrane Chromatography: Enabling the Next Generation Bioprocessing Paradigm
Webinar: High Productivity Membrane Chromatography: Enabling the Next Generation Bioprocessing Paradigm

Advantages of a fully single-use membrane-based purification process as well as high capacity flow through polishing with an inventive membrane absorber.

Webinar: Downstream Process Intensification for Virus Purification Using Membrane Chromatography
Webinar: Downstream Process Intensification for Virus Purification Using Membrane Chromatography

Improve virus purification yield, productivity & manufacturing flexibility while reducing costs via process intensification using membrane chromatography. 

Webinar: Membrane Chromatography Solutions for Single-Use, Intensified mAb Purification
Webinar: Membrane Chromatography Solutions for Single-Use, Intensified mAb Purification

Learn the benefits of a novel Protein A affinity membrane, used as a high productivity, truly single-use chromatography platform for intensified mAb purification