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P3C030D05

Placa Pellicon® 3 con membrana Ultracel®

filtration area 0.57 m2, NMWCO 30 kDa, Holdup volume 118 mL

Sinónimos:

Pellicon® 3 Cassette with Ultracel 30 kDa Membrane, D screen, 0.57 m2, Pellicon® 3 Ultracel® Membrane Cassette, Pellicon® 3 Ultrafiltration Cassette

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eCl@ss:
32031602
UNSPSC Code:
41104903
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Quality Segment

material

TPE seal, composite regenerated cellulose (CRC) , polypropylene screen, stainless steel cap (for end; polypropylene-encapsulated)

sterility

non-sterile

product line

Pellicon®

feature

holdup volume 118 mL (in feed channel)

manufacturer/tradename

Pellicon®

parameter

30 psi max. reverse press. exposure at 25 °C (for 24 hours), 4-6 L/min-m2 recirculation rate, 40 psi max. transmembrane pressure at 4-50 °C, 6.9 bar max. inlet pressure (100 psi), 80 psi max. transmembrane pressure at 4-40 °C

technique(s)

analytical sample preparation: suitable, buffer exchange: suitable, protein purification: suitable (concentration), tangential flow filtration (TFF): suitable

H

2.6 cm (1.01 in.)

L

20.6 cm (8.1 in.)

W

17.8 cm (7 in.)

filtration area

0.57 m2

membrane area

0.57 m2

gravimetric extractables

≤1500 mg/m2

matrix

Ultracel® (Membrane)

pore size

30 kDa NMWCO

pH

2-13

application(s)

mAb
recombinant protein

General description

The Pellicon® 3 Cassette with Ultracel® membrane is a high performance tangential flow filtration (TFF) device designed to support efficient ultrafiltration and diafiltration of therapeutic antibodies and other biologics. This cassette is manufactured for high product recovery, reliable flux performance, and robust cleanability. It reduces processing time while maintaining product quality. Its durable construction enables operation under demanding process conditions, including elevated pressures, and temperatures, making it an ideal choice for today′s high-titer bioprocessing applications.

Application

Pellicon® 3 Cassettes with Ultracel® 30kD Membrane D screen is manufactured to efficiently process high viscosity products. These cassettes can achieve higher concentration therapeutic protein formulations by maximizing mass transfer and managing the pressure drop created by higher viscosity. From process development through commercial production, these cassettes deliver reliable performance across various filtration applications, including:
  • Monoclonal antibodies (mAbs)
  • Recombinant and non-recombinant proteins
  • Plasma
  • Vaccine process streams

Features and Benefits

  • Rugged & reliable – ideally suited for today′s more demanding filtration processes
  • High performance – produces excellent resolution, yields and back-pressure resistance
  • Optimum product recovery – thanks to proven membrane technology
  • Void-free technology – leading-edge membranes resolve virtually any separation challenge
  • Defect-free, superior adhesion – Ultracel®uses composite membranes cast on a microporous substrate
  • Automated manufacturing – delivers unbeatable performance, consistency and reliability
  • Easy installation & care – simple to install and maintain

Analysis Note

Gravimetric Extractables: after 24 hours in water at controlled room temperature

Other Notes

These products are manufactured in a facility which adheres to Good Manufacturing Practices.

Legal Information

Pellicon is a registered trademark of Merck KGaA, Darmstadt, Germany
ULTRACEL is a registered trademark of Merck KGaA, Darmstadt, Germany

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Este artículo
P3C010C05P3C030C05P3C030D01
description

filtration area 0.57 m2, NMWCO 30 kDa, Holdup volume 118 mL

description

filtration area 0.57 m2, NMWCO 10 kDa

description

filtration area 0.57 m2, NMWCO 30 kDa

description

filtration area 0.11 m2, NMWCO 30 kDa

pore size

30 kDa NMWCO

pore size

10 kDa NMWCO

pore size

30 kDa NMWCO

pore size

30 kDa NMWCO

technique(s)

buffer exchange: suitable, analytical sample preparation: suitable, protein purification: suitable (concentration)

technique(s)

buffer exchange: suitable, analytical sample preparation: suitable, protein purification: suitable (concentration)

technique(s)

buffer exchange: suitable, protein purification: suitable (concentration), analytical sample preparation: suitable

technique(s)

analytical sample preparation: suitable, buffer exchange: suitable, protein purification: suitable (concentration)

filtration area

0.57 m2

filtration area

0.57 m2

filtration area

0.57 m2

filtration area

0.11 m2

matrix

Ultracel® (Membrane)

matrix

Ultracel® (Membrane)

matrix

Ultracel® (Membrane)

matrix

Ultracel® (Membrane)

material

polypropylene screen, TPE seal, composite regenerated cellulose (CRC) , stainless steel cap (for end; polypropylene-encapsulated)

material

composite regenerated cellulose (CRC) , polypropylene screen, TPE seal, stainless steel cap (for end; polypropylene-encapsulated)

material

stainless steel cap (for end; polypropylene-encapsulated), TPE seal, polypropylene screen, composite regenerated cellulose (CRC)

material

TPE seal, polypropylene cap (for end), polypropylene screen, composite regenerated cellulose (CRC)

parameter

30 psi max. reverse press. exposure at 25 °C (for 24 hours), 4-6 L/min-m2 recirculation rate, 80 psi max. transmembrane pressure at 4-40 °C, 6.9 bar max. inlet pressure (100 psi), 40 psi max. transmembrane pressure at 4-50 °C

parameter

4-6 L/min-m2 recirculation rate, 80 psi max. transmembrane pressure at 4-40 °C, 30 psi max. reverse press. exposure at 25 °C (for 24 hours), 6.9 bar max. inlet pressure (100 psi), 40 psi max. transmembrane pressure at 4-50 °C

parameter

6.9 bar max. inlet pressure (100 psi), 30 psi max. reverse press. exposure at 25 °C (for 24 hours), 40 psi max. transmembrane pressure at 4-50 °C, 80 psi max. transmembrane pressure at 4-40 °C, 4-6 L/min-m2 recirculation rate

parameter

40 psi max. transmembrane pressure at 4-50 °C, 4-6 L/min-m2 recirculation rate, 6.9 bar max. inlet pressure (100 psi), 80 psi max. transmembrane pressure at 4-40 °C, 30 psi max. reverse press. exposure at 25 °C (for 24 hours)


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