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Merck

K2012

Ketoprofen

meets USP testing specifications

Sinónimos:

2-(3-Benzoylphenyl)propionic acid

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Fórmula empírica (notación de Hill):
C16H14O3
Número CAS:
22071-15-4
Peso molecular:
254.28
EC Number:
244-759-8
MDL number:
MFCD00055790
UNSPSC Code:
41116107
PubChem Substance ID:
24896217
NACRES:
NA.21

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agency

USP/NF
meets USP testing specifications

Quality Level

200

form

solid

application(s)

pharmaceutical (small molecule)

SMILES string

CC(C(O)=O)c1cccc(c1)C(=O)c2ccccc2

InChI

1S/C16H14O3/c1-11(16(18)19)13-8-5-9-14(10-13)15(17)12-6-3-2-4-7-12/h2-11H,1H3,(H,18,19)

InChI key

DKYWVDODHFEZIM-UHFFFAOYSA-N

Gene Information

human ... ALB(213), IL8RA(3577), PTGS1(5742), PTGS2(5743)

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1 of 4

Este artículo
K1751I7905A3160
Ketoprofen meets USP testing specifications

Sigma-Aldrich

K2012

Ketoprofen

Ketoprofen ≥98% (TLC)

Sigma-Aldrich

K1751

Ketoprofen

Ibuprofen meets USP testing specifications

Sigma-Aldrich

I7905

Ibuprofen

Acetylsalicylic acid analytical standard

Sigma-Aldrich

A3160

Acetylsalicylic acid

Gene Information

human ... ALB(213), IL8RA(3577), PTGS1(5742), PTGS2(5743)

Gene Information

human ... ALB(213), IL8RA(3577), PTGS1(5742), PTGS2(5743)

Gene Information

human ... ALB(213), ALOX5(240), CYP1A2(1544), CYP2C9(1559), IL8RA(3577), PTGS1(5742), PTGS2(5743)
mouse ... Alox5(11689)
rat ... Alox5(25290), Ptgs1(24693)

Gene Information

human ... ITGA2B(3674), PTGS1(5742), PTGS2(5743)

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

form

solid

form

powder

form

solid

form

powder

agency

USP/NF

agency

-

agency

USP/NF, meets USP testing specifications

agency

-

application(s)

pharmaceutical (small molecule)

application(s)

-

application(s)

pharmaceutical (small molecule)

application(s)

forensics and toxicology
pharmaceutical
veterinary

Application


  • A strong, silk protein-inspired tissue adhesive with an enhanced drug release mechanism for transdermal drug delivery.: Although not exclusively focused on ketoprofen, this study details a novel adhesive for transdermal delivery, highlighting methods that could be adapted for enhancing the delivery of ketoprofen, thus being of interest to biochemists specializing in transdermal drug formulations (Fang et al., 2024).

Biochem/physiol Actions

Non-steroidal anti-inflammatory compound that is selective for COX-1.

pictograms

Skull and crossbonesEnvironment
GHS06,GHS09

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Acute 1 - Eye Irrit. 2 - Skin Irrit. 2

Clase de almacenamiento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

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Certificados de análisis (COA)

Lot/Batch Number
0000493735
0000493735
0000333417
0000333416
SLCR5202

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Elisabeth Christiansen et al.
Journal of medicinal chemistry, 54(19), 6691-6703 (2011-08-23)
The free fatty acid receptor 1 (FFA1, also known as GPR40) enhances glucose-stimulated insulin secretion from pancreatic β-cells and is recognized as an interesting new target for treatment of type 2 diabetes. Several series of selective FFA1 agonists are already
Ikram Ullah Khan et al.
International journal of pharmaceutics, 441(1-2), 809-817 (2012-12-26)
Microchannels based microfluidic systems are able to obtain monodispersed microparticles but are limited by cost, time and channel clogging. We succeeded in on the fly encapsulation of high ketoprofen contents in acrylate-based copolymer microbeads by environment friendly UV induced free
Nathalie C Newby et al.
Journal of dairy science, 96(3), 1511-1520 (2013-01-22)
Surgical correction of left displaced abomasum (LDA) is common in lactating dairy cattle. Despite the growing acceptance that abdominal surgery is painful, few cows are administered analgesia following LDA surgery. The objective of this research was to examine the effect
F Jamali et al.
Clinical pharmacokinetics, 19(3), 197-217 (1990-09-01)
Ketoprofen, a potent nonsteroidal anti-inflammatory drug (NSAID) of the 2-arylpropionic acid class, has been used clinically for over 15 years in Europe, and has recently been introduced in the United States. Although it possesses a chiral centre, with only the
M Sugiura et al.
Contact dermatitis, 43(1), 16-19 (2000-07-21)
We report 4 cases of photocontact dermatitis due to ketoprofen, a non-steroidal anti-inflammatory drug derived from propionic acid. We carried out a skin biopsy to examine the amount of ketoprofen in the eruptive skin. We investigated the cross-reactions between tiaprofenic
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