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Merck

Physico-chemical stability of astaxanthin nanodispersions prepared with polysaccharides as stabilizing agents.

International journal of food sciences and nutrition (2013-04-18)
Navideh Anarjan, Chin Ping Tan
RESUMEN

The emulsification and stabilization ability of four selected polysaccharides, namely, gum Arabic, xanthan gum, pectin and methyl cellulose, in the preparation of water-dispersible astaxanthin nanoparticles using the emulsification-evaporation technique was investigated in this study. The chemical and molecular structure of polysaccharides had significant effects (p < 0.05) on the physicochemical properties of the prepared astaxanthin nanodispersions. Among all prepared nanodispersions, sample produced and stabilized using gum Arabic showed the smallest average particle size (295 nm) and highest physical stability. The observed considerable degradation of astaxanthin in the resulting nanodispersions during processing (24-70% w/w) and storage at 10 °C for 30 d (86-96% w/w) illustrated the limited chemical stability of polysaccharide-stabilized nanodispersions.

MATERIALES
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Sigma-Aldrich
Methyl cellulose, viscosity: 4,000 cP
Sigma-Aldrich
Xanthan gum from Xanthomonas campestris
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Pectin from citrus peel, Galacturonic acid ≥74.0 % (dried basis)
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Methyl cellulose, viscosity: 15 cP, BioReagent, suitable for cell culture
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Methyl cellulose, viscosity: 1,500 cP
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Methyl cellulose, viscosity: 15 cP
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Methyl cellulose, 27.5-31.5% (Methoxyl content), viscosity: 400 cP
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Methyl cellulose, viscosity: 25 cP
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Methyl cellulose, viscosity 3000-5500 mPa.s, 2 % in H2O(20 °C)
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Methyl cellulose, meets USP testing specifications, 26.0-33.0% (methoxyl group, on Dry Basis), viscosity: 400 cP
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Methyl cellulose, 27.5-31.5% methoxyl basis
Supelco
Pectin, for use with Total Dietary Fiber Control Kit, TDF-C10
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Methyl cellulose, medium viscosity, Methoxyl content 27.5-31.5 %
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Methyl cellulose, tested according to Ph. Eur.
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Methyl cellulose, 26.0-33.0% (Methoxy group (dry basis)), meets USP testing specifications, viscosity: 1,500 cP