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Merck

RNF146 Inhibits Excessive Autophagy by Modulating the Wnt-β-Catenin Pathway in Glutamate Excitotoxicity Injury.

Frontiers in cellular neuroscience (2017-03-23)
Yuefan Yang, Peng Luo, Haoxiang Xu, Shuhui Dai, Wei Rao, Cheng Peng, Wenke Ma, Jiu Wang, Hongyu Xu, Lei Zhang, Sai Zhang, Zhou Fei
PMID28321181
RESUMEN

Glutamate induced excitotoxicity is common in diverse neurological disorders. RNF146 as an E3 ubiquitin ligase protects neurons against excitotoxicity