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CCR5

chemokine (C-C motif) receptor 5 (gene/pseudogene)

Synonyme:
CC-CKR-5, CCCKR5, CCR-5, CD195, CKR-5, CKR5, CMKBR5, IDDM22
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(1234) Summary: This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(12774) chemokine (C-C motif) receptor 5
  • Rat(117029) chemokine (C-C motif) receptor 5
  • domestic guinea pig(100716672) chemokine (C-C motif) receptor 5
  • naked mole-rat(101723738) chemokine (C-C motif) receptor 5
  • Horse(100048935) chemokine (C-C motif) receptor 5
  • cow(497017) chemokine (C-C motif) receptor 5
  • sheep(101117453) chemokine (C-C motif) receptor 5
  • domestic cat(493769) chemokine (C-C motif) receptor 5
  • chicken(420695) chemokine (C-C motif) receptor 5
  • dog(484789) chemokine (C-C motif) receptor 5
  • Domestic Rabbit(100101579) chemokine (C-C motif) receptor 5

Custom & Knockdown Gene Products

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-CCR5 antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
Anwendung
immunohistochemistry
western blot
Anti-CCR5, C-Terminal antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human
Anwendung
ELISA
western blot
Anti-CCR5 antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, pig
Anwendung
western blot
Anti-CCR5 (CD195) Antibody, clone HEK/1/85a/7a, clone HEK/1/85a/7a, from rat,
Speziesreaktivität
human
Anwendung
flow cytometry
immunocytochemistry
Anti-C-C Chemokine Receptor 5 Antibody, NT, Chemicon®, from rabbit,
Speziesreaktivität
human
Anwendung
western blot

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human CCR5,
Spezies
human
MISSION® esiRNA, targeting mouse Ccr5,
Spezies
mouse