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CRH

corticotropin releasing hormone

Synonyme:
CRF
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(1392) Summary: Corticotropin-releasing hormone is secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress. Marked reduction in this protein has been observed in association with Alzheimer disease and autosomal recessive hypothalamic corticotropin deficiency has multiple and potentially fatal metabolic consequences including hypoglycemia and hepatitis. In addition to production in the hypothalamus, this protein is also synthesized in peripheral tissues, such as T lymphocytes and is highly expressed in the placenta. In the placenta it is a marker that determines the length of gestation and the timing of parturition and delivery. A rapid increase in circulating levels of the hormone occurs at the onset of parturition, suggesting that, in addition to its metabolic functions, this protein may act as a trigger for parturition. [provided by RefSeq, Apr 2010]
  • Mouse(12918) corticotropin releasing hormone
  • Rat(81648) corticotropin releasing hormone
  • chicken(404297) corticotropin releasing hormone
  • dog(486977) corticotropin releasing hormone
  • domestic cat(692345) corticotropin releasing hormone
  • cow(280755) corticotropin releasing hormone
  • Domestic Rabbit(100301553) corticotropin releasing hormone
  • sheep(101121525) corticotropin releasing hormone
  • domestic guinea pig(100719294) corticotropin releasing hormone
  • naked mole-rat(101717831) corticotropin releasing hormone

Custom & Knockdown Gene Products

Small Molecule - Agonist

Produktnummer
Beschreibung
Spezies
Astressin, ≥90% (HPLC),
Spezies
mouse, human, rat

Small Molecule - Antagonist

Produktnummer
Beschreibung
Spezies
Corticotropin Releasing Factor Antagonist, ≥97% (HPLC),
Spezies
mouse, human, rat

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-CRH antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
western blot
Anti-Corticotropin Releasing Factor antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Speziesreaktivität
bovine, canine, frog, human, mouse, pig, rat, sheep
Anwendung
immunohistochemistry
microarray

radioimmunoassay

Proteins

Produktnummer
Beschreibung
Spezies
Corticotropin-freisetzender Faktor, Mensch, Ratte, ≥95% (HPLC), powder,
Spezies
human
Corticotropin Releasing Factor bovine, ≥90% (HPLC), Synthetic,
Spezies
cow
Corticotropin Releasing Factor, Mensch und Ratte, An immunomodulatory neuropeptide that acts to release ACTH from the anterior pituitary and stimulates the sympathetic nervous system and adrenal medulla.,
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human CRH,
Spezies
human
MISSION® esiRNA, targeting mouse Crh,
Spezies
mouse