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GAD1

glutamate decarboxylase 1 (brain, 67kDa)

Synonyme:
CPSQ1, GAD, SCP
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(2571) Summary: This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form. [provided by RefSeq, Jul 2008]
  • Mouse(14415) glutamate decarboxylase 1
  • Rat(24379) glutamate decarboxylase 1
  • sheep(101117393) glutamate decarboxylase 1 (brain, 67kDa)
  • domestic cat(493699) glutamate decarboxylase 1 (brain, 67kDa)
  • domestic guinea pig(100271904) glutamate decarboxylase 1
  • naked mole-rat(101725846) glutamate decarboxylase 1 (brain, 67kDa)
  • cow(517552) glutamate decarboxylase 1 (brain, 67kDa)
  • fruit fly(38484) Glutamic acid decarboxylase 1
  • chicken(395743) glutamate decarboxylase 1 (brain, 67kDa)
  • dog(478794) glutamate decarboxylase 1 (brain, 67kDa)

Custom & Knockdown Gene Products

ELISA

Produktnummer
Beschreibung
Spezies
Human GAD1 ELISA, for serum, plasma and cell culture supernatants,
Spezies
human

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-GAD67-Antikörper, Klon 1G10.2, clone 1G10.2, Chemicon®, from mouse,
Speziesreaktivität
human, mouse, rat
Anwendung
immunohistochemistry
western blot
Anti-GAD67-Antikörper, Klon 1G10.2, Biotin-Konjugat, clone 1G10.2, from mouse, biotin conjugate,
Speziesreaktivität
human, mouse, rat
Anwendung
immunocytochemistry
immunohistochemistry
Anti-GAD67 Antibody, clone 1G10.2 ZooMAb® Mouse Monoclonal, recombinant, expressed in HEK 293 cells,
Speziesreaktivität
human, mouse, rat
Anwendung
immunocytochemistry
immunohistochemistry

western blot
Anti-GAD1 antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
immunohistochemistry

western blot
Monoclonal Anti-GAD1 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL2911, purified immunoglobulin, buffered aqueous glycerol solution,
Speziesreaktivität
human, mouse, rat
Anwendung
immunohistochemistry
western blot

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human GAD1,
Spezies
human
MISSION® esiRNA, targeting mouse Gad1,
Spezies
mouse