GCK
glucokinase (hexokinase 4)
Synonyme:
FGQTL3, GK, GLK, HHF3, HK4, HKIV, HXKP, LGLK, MODY2
Spezies:
Human GCK (2645), Mouse Gck (103988), Rat Gck (24385), Zebrafish gck (751668), chicken GCK (430370), domestic cat GCK (100037406), dog GCK (606490), sheep GCK (101117412), cow GCK (616576), Horse GCK (100051836) ...Mehr
UniProtKB-ID:
Gen-ID:
- Human(2645) Summary: Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), maturity onset diabetes of the young, type 2 (MODY2) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI). [provided by RefSeq, Apr 2009]
- Mouse(103988) glucokinase
- Rat(24385) glucokinase
- Zebrafish(751668) glucokinase (hexokinase 4, maturity onset diabetes of the young 2)
- chicken(430370) glucokinase (hexokinase 4)
- domestic cat(100037406) glucokinase (hexokinase 4)
- dog(606490) glucokinase (hexokinase 4)
- sheep(101117412) glucokinase (hexokinase 4)
- cow(616576) glucokinase (hexokinase 4)
- Horse(100051836) glucokinase (hexokinase 4)
- naked mole-rat(101721664) glucokinase (hexokinase 4)
- domestic guinea pig(100717630) glucokinase (hexokinase 4)
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Antibodies
Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-GCK antibody produced in rabbit, Ab1, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-GCK antibody produced in rabbit, ,
Speziesreaktivität
human, mouse, rat
Anwendung
immunofluorescence
western blot
western blot
Anti-Glucokinase/GCK Antibody, clone 9G1.2, clone 9G1.2, from mouse,
Speziesreaktivität
human
Anwendung
immunohistochemistry
western blot
western blot
esiRNA
Produktnummer
Beschreibung
Spezies