METAP2
methionyl aminopeptidase 2
Synonyme:
MAP2, MNPEP, p67, p67eIF2
Spezies:
Human METAP2 (10988), Mouse Metap2 (56307), Rat Metap2 (64370), domestic cat METAP2 (101082672), naked mole-rat Metap2 (101705501), dog METAP2 (475429), domestic guinea pig Metap2 (100724502), cow METAP2 (404150), chicken METAP2 (417912), sheep METAP2 (101117320)
UniProtKB-ID:
Gen-ID:
- Human(10988) Summary: This gene is a member of the methionyl aminopeptidase family and encodes a protein that binds 2 cobalt or manganese ions. This protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent protein. Increased expression of this gene is associated with various forms of cancer and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. A pseudogene of this gene is located on chromosome 2. [provided by RefSeq, Jul 2008]
- Mouse(56307) methionine aminopeptidase 2
- Rat(64370) methionyl aminopeptidase 2
- domestic cat(101082672) methionyl aminopeptidase 2
- naked mole-rat(101705501) methionyl aminopeptidase 2
- dog(475429) methionyl aminopeptidase 2
- domestic guinea pig(100724502) methionyl aminopeptidase 2
- cow(404150) methionyl aminopeptidase 2
- chicken(417912) methionyl aminopeptidase 2
- sheep(101117320) methionyl aminopeptidase 2
- Horse(100052132) methionyl aminopeptidase 2
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Antibodies
Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-METAP2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot