PRKAB1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
Synonyme:
AMPK, HAMPKb
Spezies:
Human PRKAB1 (5564), Mouse Prkab1 (19079), Rat Prkab1 (83803), Horse PRKAB1 (100034094), sheep PRKAB1 (101107899), chicken PRKAB1 (416986), domestic cat PRKAB1 (101094051), naked mole-rat Prkab1 (101705863), cow PRKAB1 (534107), domestic guinea pig Prkab1 (100719458)
UniProtKB-ID:
Gen-ID:
- Human(5564) Summary: The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex. [provided by RefSeq, Jul 2008]
- Mouse(19079) protein kinase, AMP-activated, beta 1 non-catalytic subunit
- Rat(83803) protein kinase, AMP-activated, beta 1 non-catalytic subunit
- Horse(100034094) protein kinase, AMP-activated, beta 1 non-catalytic subunit
- sheep(101107899) protein kinase, AMP-activated, beta 1 non-catalytic subunit
- chicken(416986) protein kinase, AMP-activated, beta 1 non-catalytic subunit
- domestic cat(101094051) protein kinase, AMP-activated, beta 1 non-catalytic subunit
- naked mole-rat(101705863) protein kinase, AMP-activated, beta 1 non-catalytic subunit
- cow(534107) protein kinase, AMP-activated, beta 1 non-catalytic subunit
- domestic guinea pig(100719458) protein kinase, AMP-activated, beta 1 non-catalytic subunit
- dog(486295) protein kinase, AMP-activated, beta 1 non-catalytic subunit
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Antibodies
Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-PRKAB1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human, mouse, rat
Anwendung
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-PRKAB1 antibody produced in rabbit, ,
Speziesreaktivität
human, mouse, rat
Anwendung
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Phospho-AMPKβ1-S108 antibody produced in rabbit, ,
Speziesreaktivität
human, mouse, rat
Anwendung
immunohistochemistry
western blot
western blot
Anti-PRKAB1 Antibody, clone 2M11 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Speziesreaktivität
chimpanzee, human, mouse
Anwendung
affinity binding assay
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Phospho-AMPKβ1-S182 antibody produced in rabbit, ,
Speziesreaktivität
human
Anwendung
western blot
Proteins
Produktnummer
Beschreibung
Spezies
AMPK (α1, β1, γ1) Protein, aktiv, 10 µg, Active, recombinant, human AMPK (α1, β1, γ1) holoenzyme, comprised of full length N-terminal 6His-tagged AMPKα1, full length untagged AMPKβ1 & full length untagged AMPKγ1. For use in Kinase Assays.,
Spezies
human
AMPK (α2, β1, γ1) Protein, active, 10 µg, Active, recombinant, human AMPK (α2, β1, γ1) holoenzyme, comprised of full length N-terminal 6His-tagged AMPKα2, full length untagged AMPKβ1 & full length untagged AMPKγ1. For use in Kinase Assays.,
Spezies
human
AMPK (α1/β1/γ1), active, His tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Spezies
human
AMPK (α1/β1/γ3), active, His tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Spezies
human
esiRNA
Produktnummer
Beschreibung
Spezies