RRM1
ribonucleotide reductase M1
Synonyme:
R1, RIR1, RR1
Spezies:
Human RRM1 (6240), Mouse Rrm1 (20133), Rat Rrm1 (685579), chicken RRM1 (419081), Zebrafish rrm1 (30740), dog RRM1 (476823), cow RRM1 (505537), Horse RRM1 (100053126), domestic cat RRM1 (101097343), Domestic Rabbit RRM1 (100345823) ...Mehr
UniProtKB-ID:
Gen-ID:
- Human(6240) Summary: This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region. [provided by RefSeq, Jul 2008]
- Mouse(20133) ribonucleotide reductase M1
- Rat(685579) ribonucleotide reductase M1
- chicken(419081) ribonucleotide reductase M1
- Zebrafish(30740) ribonucleotide reductase M1 polypeptide
- dog(476823) ribonucleotide reductase M1
- cow(505537) ribonucleotide reductase M1
- Horse(100053126) ribonucleotide reductase M1
- domestic cat(101097343) ribonucleotide reductase M1
- Domestic Rabbit(100345823) ribonucleotide reductase M1
- sheep(101116171) ribonucleotide reductase M1
- naked mole-rat(101708047) ribonucleotide reductase M1
- domestic guinea pig(100728488) ribonucleotide reductase M1
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Antibodies
Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-RRM1 Antibody, clone 1E20 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Speziesreaktivität
human, monkey
Anwendung
affinity binding assay
flow cytometry
immunohistochemistry
western blot
flow cytometry
immunohistochemistry
western blot
Anti-RRM1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
Anti-RRM1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
immunohistochemistry
immunohistochemistry
Small Molecule - Inhibitor
Produktnummer
Beschreibung
Spezies
Gemcitabin-Hydrochlorid -hydrochlorid, United States Pharmacopeia (USP) Reference Standard,
Spezies
human