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SLC1A2

solute carrier family 1 (glial high affinity glutamate transporter), member 2

Synonyme:
EAAT2, GLT-1
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(6506) Summary: This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis. Alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Sep 2010]
  • Mouse(20511) solute carrier family 1 (glial high affinity glutamate transporter), member 2
  • Rat(29482) solute carrier family 1 (glial high affinity glutamate transporter), member 2
  • naked mole-rat(101701278) solute carrier family 1 (glial high affinity glutamate transporter), member 2
  • domestic guinea pig(100731435) solute carrier family 1 (glial high affinity glutamate transporter), member 2
  • chicken(423156) solute carrier family 1 (glial high affinity glutamate transporter), member 2
  • dog(403750) solute carrier family 1 (glial high affinity glutamate transporter), member 2
  • cow(541119) solute carrier family 1 (glial high affinity glutamate transporter), member 2

Custom & Knockdown Gene Products

Small Molecule - Antagonist

Produktnummer
Beschreibung
Spezies
L-trans-Pyrrolidine-2,4-dicarboxylic acid, ≥98%,
Spezies
rat
Dihydrokainic acid, ≥98% (HPLC), powder,
Spezies
rat, human
(±)-AMPA, solid,
Spezies
rat
Kainic acid monohydrate, ≥99% (TLC),
Spezies
human, mouse, rat
(Aminomethyl)phosphonsäure, 99%,
Spezies
rat, human

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Glialer Anti-Glutamat-Transporter-Antikörper, serum, Chemicon®,
Speziesreaktivität
human, mouse, rat
Anwendung
immunofluorescence
immunohistochemistry

western blot
Anti-SLC1A2 antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Anwendung
immunohistochemistry
western blot
Anti-Excitatory amino acid transporter 2 Antibody, clone G6, clone G6, from mouse,
Speziesreaktivität
human, mouse, rat
Anwendung
immunocytochemistry
immunohistochemistry

western blot
Anti-SLC1A2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
immunohistochemistry
Anti-Excitatory Amino Acid Transporter (GLT-1) Rabbit pAb, liquid, Calbiochem®,
Speziesreaktivität
rat
Anwendung

Small Molecule - Inhibitor

Produktnummer
Beschreibung
Spezies
Dihydrokainic acid, ≥98% (HPLC), powder,
Spezies
rat, human
(Aminomethyl)phosphonsäure, 99%,
Spezies
rat, human
L-Glutaminsäure, ReagentPlus®, ≥99% (HPLC),
Spezies
rat, human
L-Glutaminsäure, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%,
Spezies
rat, human
L-Glutaminsäure, BioUltra, ≥99.5% (NT),
Spezies
rat, human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human SLC1A2,
Spezies
human