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TPM1

tropomyosin 1 (alpha)

Synonyme:
C15orf13, CMD1Y, CMH3, HTM-alpha, LVNC9, TMSA
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(7168) Summary: This gene is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in this gene are associated with type 3 familial hypertrophic cardiomyopathy. [provided by RefSeq, Jul 2008]
  • Mouse(22003) tropomyosin 1, alpha
  • Rat(24851) tropomyosin 1, alpha
  • chicken(396366) tropomyosin 1 (alpha)
  • Zebrafish(393908) tropomyosin 1 (alpha)
  • domestic cat(101091450) tropomyosin 1 (alpha)
  • dog(478332) tropomyosin 1 (alpha)
  • naked mole-rat(101714552) tropomyosin 1 (alpha)
  • sheep(100145865) tropomyosin 1 (alpha)
  • domestic guinea pig(100717160) tropomyosin 1 (alpha)
  • cow(281544) tropomyosin 1 (alpha)

Custom & Knockdown Gene Products

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-TPM1, IgG fraction of antiserum,
Speziesreaktivität
dog, guinea pig, human, mouse, rabbit, rat
Anwendung
immunohistochemistry
western blot
Anti-TPM1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
Anti-TPM1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
Anti-Tropomyosin Antibody, clone 15D12.2, clone 15D12.2, from mouse,
Speziesreaktivität
human, mouse, rat
Anwendung
immunohistochemistry
western blot
Anti-Tropomyosin Antibody, clone 1C5 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Speziesreaktivität
human, mouse
Anwendung
flow cytometry
immunocytochemistry

immunohistochemistry

western blot

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human TPM1,
Spezies
human
MISSION® esiRNA, targeting mouse Tpm1,
Spezies
mouse