The molecular weight of this material has not been tested on a lot-to-lot basis. However, historical data indicates a range of 150-2,000 base pairs. This corresponds to an approximate molecular weight range of 99,000 - 1,320,000 daltons.
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P1537
Polyadenylic acid-Polyuridylic acid sodium salt
double-stranded homopolymer
Synonym(e):
Poly[A]•Poly[U]
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| Größe/SKU | Verfügbarkeit | Preis |
|---|---|---|
10 mg | Warenkorb auf Verfügbarkeit prüfen | € 349,00 |
Über diesen Artikel
Form:
powder
Storage temp.:
−20°C
Technischer Dienst
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Unterstützung erhaltenQuality Segment
form
powder
storage temp.
−20°C
SMILES string
[P](=O)(OC[C@H]3O[C@H]([C@@H]([C@@H]3O)O)[n]4c5ncnc(c5nc4)N)(O)O.[P](=O)(OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)N2C=CC(=O)NC2=O)(O)O
InChI
1S/C10H14N5O7P.C9H13N2O9P/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(22-10)1-21-23(18,19)20;12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18/h2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,20);1-2,4,6-8,13-14H,3H2,(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,10-;4-,6-,7-,8-/m11/s1
InChI key
VGQHQOKIMNKUEF-ZLOOHWKQSA-N
Application
Polyadenylic acid-Polyuridylic acid (polyAU) is a double stranded homodimer studied for potential therapeutic activity, especially when coupled with radiotherapy. PolyA/U is used in comparative physiochemical studies with other duplex and single-stranded polymers such as poly-A and poly-U.
Other Notes
Double stranded homopolymer
1 of 1
Dieser Artikel | |||
|---|---|---|---|
| description double-stranded homopolymer | description - | description Known to induce interferon production. Hypochromicity: ≥40% at 248 nm. Extinction coefficient = 5000 M-1cm-1 at 260 nm, pH 7.0. | description - |
| Quality Level 200 | Quality Level 200 | Quality Level 100 | Quality Level 300 |
| form powder | form lyophilized powder | form powder | form powder |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
Lagerklasse
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
PSA (Persönliche Schutzausrüstung)
Eyeshields, Gloves, type N95 (US)
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what is the molecular weight of Polyadenylic acid-Polyuridylic acid sodium salt
1 answer-
Helpful?
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What is the average base pair length for this product
1 answer-
The product specification does not include a base pair length, and it is not determined in quality control testing. The best estimate is that the polymer is a mixture of different lengths ranging from 150 base pairs to 2,000 base pairs. Users requiring more specificity of the base pair lengths may need to determine it using gel electrophoresis.
Helpful?
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I'd like to know the homogeneity of this product, or at least the % A:U base pairing. My application is sensitive to high mismatch and single strand RNA content and I'm hoping this is at least 85% A:U base paired.
1 answer-
Unfortunately, the homogeneity and A:U ratio are not determined for this product. The material is prepared by separately preparing polyA and polyU strands by an enzymatic method. The individual polyA and polyU strands are purified to remove low molecular weight species then annealed by heating, followed by a slow cooling process. Historical information indicates an approximate starting ratio of 1:2 molar concentration of Poly(A) to Poly(U), respectively. There is an estimated sodium content of 5 - 6%.
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