This product has a phosphate group at the 5' end. No information is available regarding the ability of this product to be sensed by cellular RNA sensors.
Fortfahren mit
P4903
poly(C)
Synonym(e):
Polycytidylsäure Kaliumsalz, Poly(C) Kaliumsalz
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Über diesen Artikel
Form:
powder
Storage temp.:
−20°C
Preise und Verfügbarkeit sind derzeit nicht verfügbar.
Technischer Dienst
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Unterstützung erhaltenPreparation Note
Prepared from CDP using polynucleotide phosphorylase
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Dieser Artikel | |||
|---|---|---|---|
| description - | description γ-irradiated, 10% Poly (I:C) with buffer salts, TLR ligand tested | description 10% Poly (I:C) with buffer salts, TLR ligand tested | description lyophilized powder |
| Quality Level 200 | Quality Level 200 | Quality Level 300 | Quality Level 200 |
| form powder | form - | form lyophilized powder | form lyophilized powder |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
Lagerklasse
11 - Combustible Solids
Was ist los?
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
PSA (Persönliche Schutzausrüstung)
Eyeshields, Gloves, type N95 (US)
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What structure is on the 5' end of this RNA (5' monophosphate?) and is this known to be sensed by any cellular RNA sensors?
1 answer-
Helpful?
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What would be the ideal buffer to dissolve the poly(C) in for ideal long-term storage?
1 answer-
The solubility of this product is tested in water at approximately 20 mg/mL. The solubility has not been tested in a buffer solution. However, the Polyuridylic acid potassium salt, P9528, offers a datasheet that notes the material may not be completely soluble in Tris buffer at 1 mg/mL.
Helpful?
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What is the size range? How many nucleotides per molecule?
1 answer-
Unfortunately, the particle size range and nucleotides number are not tested as per the COA of P4903: https://www.sigmaaldrich.com/certificates/sapfs/PROD/sap/certificate_pdfs/COFA/Q14/P4903-100MG0000303636.pdf
There is a reference value for degree of polymerization (DP) available to roughly estimate the nucleotides number, which is ~485. The value could vary lot by lot.Helpful?
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