SAB2500331

Anti-DUSP1 antibody produced in goat

affinity isolated antibody, buffered aqueous solution

• Synonym(e): Anti-CL100, Anti-Dual specificity phosphatase 1, Anti-HVH1, Anti-MKP-1, Anti-PTPN10
• UNSPSC Code: 12352203
• NACRES: NA.41
• MDL number: MFCD01092411
• Conjugate: unconjugated
• Clone: polyclonal
• Application: ELISA (i), IHC, WB
• Citations: 11

Eigenschaften

• biological source: goat
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• species reactivity: human, mouse, rat
• technique(s): immunohistochemistry: suitable, indirect ELISA: suitable, western blot: suitable
• UniProt accession no.: P28562
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... DUSP1(1843)

Beschreibung

General description

Dual specificity phosphatase 1 (DUSP1) is a protein phosphatase. The gene encoding it is localized on human chromosome 5q35.1.

Immunogen

Peptide with sequence SYLQSPITTSPSC from the C Terminus of the protein sequence according to NP_004408.1.

Application

Anti-DUSP1 antibody produced in goat has been used for Western blotting.

Biochem/physiol Actions

Dual specificity phosphatase 1 (DUSP1) modulates the activity of mitogen-activated protein kinase (MAPK). It targets and dephosphorylates extracellular signal-regulated kinases 1 and 2 (ERK 1/2). During cellular responses to oxidative stress, the activity of DUSP1 is regulated by p53. Overexpression of the protein has been associated with various tumors.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklasse: 10 - Combustible liquids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable