SAB6012011

Anti COPS8 Antibody, clone 23GB3100, Rabbit Monoclonal

clone 23GB3100, recombinant rabbit monoclonal, expressed in HEK293 cells

• Synonym(e): COP9, CSN8, HCOP9, SGN8
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• Conjugate: unconjugated
• Clone: 23GB3100, recombinant monoclonal
• Application: FACS, IF, WB
• Citations: -

Eigenschaften

• biological source: rabbit (Monoclonal)
• Quality Segment: 100
• recombinant: expressed in HEK 293 cells
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: 23GB3100, recombinant monoclonal
• form: buffered aqueous glycerol solution
• mol wt: 23 kDa
• species reactivity: rat, human
• packaging: vial of 1.5 mL
• enhanced validation: recombinant expression; Learn more about Antibody Enhanced Validation
• sustainability: Sustainability features
• concentration: 0.2 mg/ml
• technique(s): flow cytometry: 1:2000, immunofluorescence: 1:100-:1000, western blot: 1:1,000-1:5,000
• isotype: IgG
• Ensembl | human accession no.: ENSG00000198612
• NCBI accession no.: NP_006701.1
• UniProt accession no.: Q99627
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... COPS8(10920)

Beschreibung

General description

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The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]

Immunogen

A synthesized peptide corresponding to a sequence within amino acids 180-209 of human CSN8 [NP_006701.1].

Physical form

Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.

Other Notes

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.

Sicherheitshinweise

• Lagerklasse: 10 - Combustible liquids
• Flammpunkt (°F): 572.0 °F
• Flammpunkt (°C): 300 °C