SML0424

ST247

≥98% (HPLC)

• Synonym(e): 3-[[[4-(Hexylamino)-2-methoxyphenyl]amino]sulfonyl]-2-thiophenecarboxylic acid methyl ester
• Empirische Formel (Hill-System): C₁₉H₂₆N₂O₅S₂
• CAS-Nummer: 1356497-91-0
• Molekulargewicht: 426.55
• UNSPSC Code: 12352200
• PubChem Substance ID: 329825419
• NACRES: NA.77
• eCl@ss: 32160701
• Assay: ≥98% (HPLC)
• Form: powder

Eigenschaften

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 10 mg/mL (clear solution)
• storage temp.: 2-8°C
• SMILES string: CCCCCCNc1ccc(NS(=O)(=O)c2ccsc2C(=O)OC)c(OC)c1
• InChI: 1S/C19H26N2O5S2/c1-4-5-6-7-11-20-14-8-9-15(16(13-14)25-2)21-28(23,24)17-10-12-27-18(17)19(22)26-3/h8-10,12-13,20-21H,4-7,11H2,1-3H3
• InChI key: MRWCGEOYGFZZCJ-UHFFFAOYSA-N

Beschreibung

Biochem/physiol Actions

ST247 is a PPAR β/δ inverse agonist.

ST247 is a PPAR β/δ selective inverse agonist. The compound is based on the structure of GSK0660, and is 10-fold more potent in blocking the transcription of endogenous target genes: ST247 IC₅₀ = 19 nm vs. GSK0660 IC₅₀ = 210 nM.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• WGK: WGK 3