SML3050

Olsalazine sodium

• Synonym(e): 5,5′-Azodisalicylic acid sodium, Olsalazine sodium, 3,3´-Azobis(6-hydroxybenzoic acid) sodium, 5,5′-azobis(salicylic acid) sodium, C.I. Mordant Yellow 5; 3,3′-dicarboxy-4,4′-dihydroxyazobenzene sodium, azodisal sodium
• Empirische Formel (Hill-System): C₁₄H₈N₂O₆ · 2Na
• CAS-Nummer: 6054-98-4
• Molekulargewicht: 346.20
• UNSPSC Code: 12352200
• NACRES: NA.24
• Assay: ≥98% (HPLC)
• Form: powder

Eigenschaften

• assay: ≥98% (HPLC)
• Quality Segment: 100
• form: powder
• color: white to beige
• solubility: H₂O: 2 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: [Na+].[Na+].N(=N\c2cc(c(cc2)[O-])C(=O)O)/c1cc(c(cc1)[O-])C(=O)O
• InChI: 1S/C14H10N2O6.2Na/c17-11-3-1-7(5-9(11)13(19)20)15-16-8-2-4-12(18)10(6-8)14(21)22;;/h1-6,17-18H,(H,19,20)(H,21,22);;/q;2*+1/p-2/b16-15+;;
• InChI key: ZJEFYLVGGFISGT-VRZXRVJBSA-L

Beschreibung

Biochem/physiol Actions

Olsalazine is an anti-inflammatory drug used in inflammatory bowel disease and ulcerative colitis treatments. It is a pro-drug of 5-aminosalicylic acid (mesalamine) that it is converted by the bacteria in the colon to mesalamine. Olsalazine (5-aminosalicylic acid) is consider as a broad-spectrum anticancer agent. Additionally, olsalazine increases both eEF1A2 and utrophin A levels in in C2C12 myoblasts (relevant to Duchenne muscular dystrophy).

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable