SML3387

Rilpivirine

≥98% (HPLC), NNRTI inhibitor, powder

• Synonym(e): 4-[[4-[[4-[(1E)-2-Cyanoethenyl]-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitrile, R 278474, TMC 278
• Empirische Formel (Hill-System): C₂₂H₁₈N₆
• CAS-Nummer: 500287-72-9
• Molekulargewicht: 366.42
• NACRES: NA.77
• UNSPSC Code: 51111800
• MDL number: MFCD11046372
• Assay: ≥98% (HPLC)
• Form: powder

Eigenschaften

• Produktname: Rilpivirine, ≥98% (HPLC)
• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: CC1=CC(=CC(=C1NC2=NC(=NC=C2)NC3=CC=C(C=C3)C#N)C)/C=C/C#N
• InChI: 1S/C22H18N6/c1-15-12-18(4-3-10-23)13-16(2)21(15)27-20-9-11-25-22(28-20)26-19-7-5-17(14-24)6-8-19/h3-9,11-13H,1-2H3,(H2,25,26,27,28)/b4-3+
• InChI key: YIBOMRUWOWDFLG-ONEGZZNKSA-N

Beschreibung

Biochem/physiol Actions

Nonnucleoside reverse transcriptase inhibitor (NNRTI); anti-retroviral

Rilpivirine is a next generation nonnucleoside reverse transcriptase inhibitor (NNRTI), It has been shown to be active against many HIV strains with mutations that confer resistance to the first-generation NNRTIs.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable