SML3940

KNX-002

≥98% (HPLC)

• Synonym(e): N-[1-(4-Methoxyphenyl)cyclopropyl]-3-(2-thienyl)-1H-pyrazole-4-methanamine
• Empirische Formel (Hill-System): C₁₈H₁₉N₃OS
• CAS-Nummer: 1029644-35-6
• Molekulargewicht: 325.43
• UNSPSC Code: 12352200
• NACRES: NA.21
• eCl@ss: 32150313
• Assay: ≥98% (HPLC)
• Form: powder

Eigenschaften

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: COC1=CC=C(C2(CC2)NCC3=CNN=C3C4=CC=CS4)C=C1
• InChI: 1S/C18H19N3OS/c1-22-15-6-4-14(5-7-15)18(8-9-18)19-11-13-12-20-21-17(13)16-3-2-10-23-16/h2-7,10,12,19H,8-9,11H2,1H3,(H,20,21)
• InChI key: CXRMCTBDMZVPNE-UHFFFAOYSA-N

Beschreibung

Biochem/physiol Actions

Cell penetrant, potent and selective inhibitor of Plasmodium falciparum myosin A (PfMyoA) and Toxoplasma gondii myosin A (TgMyoA).



KNX-002 is a cell penetrant, potent and selective inhibitor of Plasmodium falciparum myosin A (PfMyoA) and Toxoplasma gondii myosin A (TgMyoA) that has no or little effect on the vertebrate myosins tested. KNX-002 obstructs efficient ATP hydrolysis thus inhibiting motor activity. KNX-002 inhibits parasite motility and growth.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable