SML4036

AN3661

≥98% (HPLC)

• Synonym(e): 1,3-Dihydro-1-hydroxy-2,1-benzoxaborole-7-propanoic acid, 3-(1-Hydroxy-1,3-dihydro-2,1-benzoxaborol-7-yl)propanoic acid; 3-(1-Hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-7-yl)propanoicacid
• Empirische Formel (Hill-System): C₁₀H₁₁BO₄
• CAS-Nummer: 1268335-33-6
• Molekulargewicht: 206.00
• MDL number: MFCD22393432
• NACRES: NA.21
• UNSPSC Code: 12352200
• Assay: ≥98% (HPLC)
• Form: powder

Eigenschaften

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: OC(CCC1=CC=CC2=C1B(OC2)O)=O
• InChI: 1S/C10H11BO4/c12-9(13)5-4-7-2-1-3-8-6-15-11(14)10(7)8/h1-3,14H,4-6H2,(H,12,13)
• InChI key: CEVOKIPNIZQANN-UHFFFAOYSA-N

Beschreibung

Biochem/physiol Actions

Boron containing antimalarial agent that targets Plasmodium falciparum CPSF3 (cleavage and polyadenylation specific factor 3).
AN3661 is a boron containing antimalarial agent that targets Plasmodium falciparum CPSF3 (cleavage and polyadenylation specific factor 3). AN3661potently inhibits Plasmodium falciparum laboratory-adapted strains (mean IC50=32 nM). Also, AN3661 inhibits T. gondii growth in human cells at low micromolar concentrations.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable