SML4438

5-TAMRA-Alkyne

≥98% (HPLC)

• Synonym(e): 5-Carboxytetramethylrhodamine, 9-[2-Carboxy-4-[(2-propyn-1-ylamino)carbonyl]phenyl]-3,6-bis(dimethylamino)-xanthylium inner salt, Propargylamide, TAMRA-Alkyne isomer 5
• Empirische Formel (Hill-System): C₂₈H₂₅N₃O₄
• CAS-Nummer: 945928-17-6
• Molekulargewicht: 467.52
• UNSPSC Code: 12352200
• Assay: ≥98% (HPLC)
• Form: powder
• Storage condition: desiccated, protect from light

Eigenschaften

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated, protect from light
• color: red to very dark purple
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: -10 to -25°C

Beschreibung

Biochem/physiol Actions

TAMRA-Alkyne is a cell-permeable, and photostable bioorthogonal probe for the high-fidelity covalent labeling of azide-functionalized biomolecules. This tool leverages the bright, orange-red fluorescence (λex/λem ~546 nm/579 nm) of an isomerically pure 5-TAMRA core and the specificity of copper-catalyzed click chemistry. It is specifically designed as a compact, fluorescent alkyne for situations where larger, PEGylated probes might introduce steric interference or are otherwise undesirable, offering a minimal steric footprint for probing constrained molecular environments. While TAMRA-alkyne’s hydrophobicity necessitates rigorous protocols to manage non-specific binding, it remains a valuable tool for fixed-cell imaging where a small tag is paramount for achieving high-resolution visualization.

Disclaimer

Hygroscopic, Store with desiccant

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable