BCR177R

Pyrene

Name: Pyrene
Brand: SIAL
Price: 262 EUR

BCR^®, certified reference material

Synonym(s):

Benzo[def]phenanthrene

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10 MG

€ 262,00

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About This Item

Empirical Formula (Hill Notation):

C₁₆H₁₀

CAS Number:

129-00-0

Molecular Weight:

202.25

Beilstein:

1307225

EC Number:

204-927-3

MDL number:

MFCD00004136

UNSPSC Code:

41116107

PubChem Substance ID:

329773798

NACRES:

NA.24

Key Documents

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grade

certified reference material

Agency

BCR^®

manufacturer/tradename

JRC

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

145-148 °C (lit.)

format

neat

storage temp.

2-8°C

SMILES string

c1cc2ccc3cccc4ccc(c1)c2c34

InChI

1S/C16H10/c1-3-11-7-9-13-5-2-6-14-10-8-12(4-1)15(11)16(13)14/h1-10H

InChI key

BBEAQIROQSPTKN-UHFFFAOYSA-N

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This Item	18868	82648	48570
BCR177R Pyrene	Supelco 18868 Pyrene	Sigma-Aldrich 82648 Pyrene	Supelco 48570 Pyrene
technique(s) HPLC: suitable, gas chromatography (GC): suitable	technique(s) HPLC: suitable, gas chromatography (GC): suitable	technique(s) -	technique(s) HPLC: suitable, gas chromatography (GC): suitable
format neat	format neat	format -	format neat
grade certified reference material	grade certified reference material, TraceCERT^®	grade for fluorescence, puriss. p.a.	grade analytical standard
storage temp. 2-8°C	storage temp. -	storage temp. -	storage temp. 2-30°C
manufacturer/tradename JRC	manufacturer/tradename Manufactured by: Sigma-Aldrich Production GmbH, Switzerland	manufacturer/tradename -	manufacturer/tradename -
agency BCR^®	agency -	agency -	agency -

General description

Pyrene belongs to polycyclic aromatic hydrocarbon group. These are organic compounds which have two or more fused benzene rings in linear, angular and cluster arrangements. Pyrene is a four ring PAH.[1]

This compound is listed in the SVHC (Substances of very high concern) candidate list of ECHA (European Chemicals Agency)

Analysis Note

For more information please see:
BCR177R

Legal Information

BCR is a registered trademark of European Commission

Pictograms

GHS09

Signal Word

Warning

Hazard Statements

H410

Precautionary Statements

P273 - P391 - P501

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

435.2 °F

Flash Point(C)

224 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

EU REACH SVHC Candidate List

CAS No.

129-00-0

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Yanna Liang

Pyrene Degradation by Mycobacterium Sp Kms: Biochemical Pathway, Enzymatic Mechanisms, and Humic Acid Effect, 1- 4 (2010)

Intramolecular pyrene excimer fluorescence: a probe of proximity and protein conformational change.

S S Lehrer

Methods in enzymology, 278, 286-295 (1997-01-01)

Pyrene-functionalized oligonucleotides and locked nucleic acids (LNAs): tools for fundamental research, diagnostics, and nanotechnology.

Michael E Østergaard et al.

Chemical Society reviews, 40(12), 5771-5788 (2011-04-14)

Pyrene-functionalized oligonucleotides (PFOs) are increasingly explored as tools in fundamental research, diagnostics and nanotechnology. Their popularity is linked to the ability of pyrenes to function as polarity-sensitive and quenchable fluorophores, excimer-generating units, aromatic stacking moieties and nucleic acid duplex intercalators.

Pyrene-labeled lipids as tools in membrane biophysics and cell biology.

Pentti Somerharju

Chemistry and physics of lipids, 116(1-2), 57-74 (2002-07-03)

Pyrene is one of the most frequently used lipid-linked fluorophores. Its most characteristic features are a long excited state lifetime and (local) concentration-dependent formation of excimers. Pyrene is also hydrophobic and thus does not significantly distort the conformation of the

Development of a robust model system of FRET using base surrogates tethering fluorophores for strict control of their position and orientation within DNA duplex.

Tomohiro Kato et al.

Journal of the American Chemical Society, 135(2), 741-750 (2012-12-18)

Although distance dependence of Förster resonance energy transfer (FRET) is well-studied and FRET has been extensively applied as "molecular ruler", only limited examples of orientation-dependent FRET have been reported. To create a robust FRET system that precisely reflects the orientation

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