G4635

Gitoxigenin

• Synonym(s): 16β-Hydroxydigitoxigenin, 3β,14,16β,21-Tetrahydroxy-20(22)-norcholenic acid lactone, 3β,14,16β-Trihydroxy-5β,20(22)-cardenolide, 5β,20(22)-Cardenolide-3β,14,16β-triol
• Empirical Formula (Hill Notation): C₂₃H₃₄O₅
• CAS Number: 545-26-6
• Molecular Weight: 390.51
• PubChem Substance ID: 24895182
• UNSPSC Code: 12352200
• EC Number: 208-886-2
• MDL number: MFCD00021174
• Beilstein/REAXYS Number: 96483

Properties

• storage temp.: −20°C
• SMILES string: [H][C@]12CC[C@]3([H])[C@]([H])(CC[C@]4(C)[C@H]([C@@H](O)C[C@]34O)C5=CC(=O)OC5)[C@@]1(C)CC[C@H](O)C2

Description

Biochem/physiol Actions

Structure-activity relationships for 16β-substituted digitoxigenins as inhibitors of Na⁺/K⁺ ATPases.

Safety Information

• Pictograms: GHS06
• Signal Word: Danger
• Hazard Codes: H301 + H311 + H331
• Precautionary Statements: P261 - P264 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• PPE (personal protective equipment): Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges