This product may be stored at room temperature.
I5627
Isoprenaline hydrochloride
≥98.5% (TLC), powder, β-adrenoceptor agonist
Synonym(s):
(±)-Isoproterenol hydrochloride, 1-(3′,4′-Dihydroxyphenyl)-2-isopropylaminoethanol hydrochloride, N-Isopropyl-DL-noradrenaline hydrochloride
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5 G
€ 55,60
25 G
€ 223,00
100 G
€ 534,00
About This Item
Empirical Formula (Hill Notation):
C11H17NO3 · HCl
CAS Number:
Molecular Weight:
247.72
Beilstein:
3917363
EC Number:
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
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Product Name
Isoprenaline hydrochloride,
Quality Level
mp
165-175 °C (dec.) (lit.)
originator
Sanofi Aventis
SMILES string
Cl.CC(C)NCC(O)c1ccc(O)c(O)c1
InChI
1S/C11H17NO3.ClH/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8;/h3-5,7,11-15H,6H2,1-2H3;1H
InChI key
IROWCYIEJAOFOW-UHFFFAOYSA-N
Gene Information
human ... ADRB1(153), ADRB2(154), ADRB3(155)
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Related Categories
1 of 4
This Item | I0599990 | 1351005 | BP205 |
|---|---|---|---|
| Quality Level 200 | Quality Level - | Quality Level - | Quality Level - |
| originator Sanofi Aventis | originator - | originator - | originator - |
| mp 165-175 °C (dec.) (lit.) | mp 165-175 °C (dec.) (lit.) | mp 165-175 °C (dec.) (lit.) | mp 165-175 °C (dec.) (lit.) |
| Gene Information human ... ADRB1(153), ADRB2(154), ADRB3(155) | Gene Information human ... ADRB1(153), ADRB2(154), ADRB3(155) | Gene Information human ... ADRB1(153), ADRB2(154), ADRB3(155) | Gene Information human ... ADRB1(153), ADRB2(154), ADRB3(155) |
Biochem/physiol Actions
β-adrenoceptor agonist; increases cytosolic cAMP.
Features and Benefits
This compound is featured on the β-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
Other Notes
For research use only
Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Na Tian et al.
Diabetes, 69(7), 1355-1367 (2020-04-17)
Obesity has recently become a prevalent health threat worldwide. Although emerging evidence has suggested a strong link between the pentose phosphate pathway (PPP) and obesity, the role of transketolase (TKT), an enzyme in the nonoxidative branch of the PPP that
Aaron M Ring et al.
Nature, 502(7472), 575-579 (2013-09-24)
G-protein-coupled receptors (GPCRs) are integral membrane proteins that have an essential role in human physiology, yet the molecular processes through which they bind to their endogenous agonists and activate effector proteins remain poorly understood. So far, it has not been
Jiao Li et al.
PloS one, 8(3), e58334-e58334 (2013-03-28)
Here we investigate how ß-adrenergic stimulation of the heart alters regulation of ryanodine receptors (RyRs) by intracellular Ca(2+) and Mg(2+) and the role of these changes in SR Ca(2+) release. RyRs were isolated from rat hearts, perfused in a Langendorff
Eric M Jones et al.
eLife, 9 (2020-10-22)
The >800 human G protein-coupled receptors (GPCRs) are responsible for transducing diverse chemical stimuli to alter cell state- and are the largest class of drug targets. Their myriad structural conformations and various modes of signaling make it challenging to understand
Michael Schwarzl et al.
Critical care medicine, 41(12), e401-e410 (2013-08-22)
We tested whether mild hypothermia impacts on circulatory and respiratory dysfunction during experimental endotoxemia. Randomized controlled prospective experimental study. Large animal facility, Medical University of Graz, Austria. Thirteen anesthetized and mechanically ventilated pigs. Lipopolysaccharide was administered for 4 hours. With
Related Content
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At what temperature do I store Isoprenaline hydrochloride?
1 answer-
Helpful?
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What is the best way to store aliquots (water solution)? Would -20C work?
1 answer-
The stability of this product in solution has not been determined. However, 10 mM stock solutions prepared in water and protected from light are expected to be stable when stored in aliquots at -20°C for at least 2 months. Avoid repeated freeze/thaw cycles. Note that solutions stored in alkaline conditions will rapidly degrade.
Helpful?
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how to dissolve the I5627-5G(isoprenaline)?
1 answer-
As mentioned on the Product Datasheet, this product is soluble in water at (50 mg/ml), yielding clear to slightly hazy, colorless to yellow or faint pink solution. The solubility in water has also been reported at 333 mg/ml. It is soluble in ethanol at 20 mg/ml.
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