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Merck

M3409

Magnesium sulfate solution

Molecular Biology, 1.00 M±0.04 M

Synonym(s):

Magnesium Sulphate, Magnesium(II) sulfate, MgSO4

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About This Item

Empirical Formula (Hill Notation):
MgSO4
CAS Number:
Molecular Weight:
120.37
NACRES:
NA.31
PubChem Substance ID:
UNSPSC Code:
12352302
MDL number:
Grade:
Molecular Biology
Form:
liquid

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Product Name

Magnesium sulfate solution, Molecular Biology, 1.00 M±0.04 M

InChI

1S/Mg.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2

SMILES string

[Mg++].[O-]S([O-])(=O)=O

InChI key

CSNNHWWHGAXBCP-UHFFFAOYSA-L

grade

Molecular Biology

sterility

0.2 μm filtered

form

liquid

concentration

1.00 M±0.04 M

cation traces

heavy metals (as Pb): ≤5 ppm

foreign activity

DNase, RNase, nickase and protease, none detected

Quality Level

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This Item
83266
form

liquid

form

liquid

Quality Level

200

Quality Level

200

grade

for molecular biology

grade

for molecular biology

cation traces

heavy metals (as Pb): ≤5 ppm

cation traces

Al: ≤1 mg/kg, As: ≤0.1 mg/kg, Ba: ≤1 mg/kg, Bi: ≤1 mg/kg, Ca: ≤20 mg/kg, Cd: ≤1 mg/kg, Co: ≤1 mg/kg, Cr: ≤1 mg/kg, Cu: ≤1 mg/kg, Fe: ≤1 mg/kg, K: ≤20 mg/kg, Li: ≤1 mg/kg, Mn: ≤1 mg/kg, Mo: ≤1 mg/kg, Na: ≤20 mg/kg, Ni: ≤1 mg/kg, Pb: ≤1 mg/kg, Sr: ≤1 mg/kg, Zn: ≤1 mg/kg

sterility

0.2 μm filtered

sterility

-

concentration

1.00 M±0.04 M

concentration

2.5 M in H2O

Application

Magnesium sulfate solution has been used:
  • as a component in super optimal broth with catabolite repression (SOC) medium for culturing Escherichia coli[1]
  • as a component in transition media for culturing human umbilical vein endothelial cells (HUVEC)[2]]
  • as a component in M9 buffer for worm fixation prior to nuclei extraction[3]

Biochem/physiol Actions

Magnesium sulfate has anti-convulsant, anti-inflammatory and vasodilatory properties. Magnesium sulfate relaxes smooth muscles.[4] In acute asthma patients, use both intravenous and nebulization of magnesium sulfate as additive treatment improves pulmonary function.[4][5] Magnesium sulfate reduces preterm labor in high risk pregnant women.[4]

Preparation Note

Prepared in 18 megohm water

Storage Class

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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RNA Chromatin Immunoprecipitation (RNA-ChIP) in Caenorhabditis elegans
Cecere G and Grishok A
Bio-protocol, 4(24), e1358-e1358 (2014)
Method for multiplexing CRISPR/Cas9 in Saccharomyces cerevisiae using artificial target DNA sequences
Giersch RM and Finnigan GC
Bio-protocol, 7(18), 321-330 (2017)
Estrogen decreases TNF-alpha and oxidized LDL induced apoptosis in endothelial cells
Florian M and Magder S
Steroids, 73(1), 47-58 (2008)
The value of magnesium sulfate nebulization in treatment of acute bronchial asthma during pregnancy
Badawy MSH and Hassanin IMA
The Egyptian journal of chest diseases and tuberculosis, 63(2), 285-289 (2014)
Lex W Doyle
Current opinion in pediatrics, 24(2), 154-159 (2012-01-10)
Antenatal magnesium sulfate may reduce the excessive rates of cerebral palsy in survivors of very preterm birth. There are five randomized controlled trials of magnesium sulfate therapy given to the mother prior to very preterm birth which have reported neurological

Questions

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  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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