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Merck

P0381

Pyrogallol

≥98% (HPLC)

Synonym(s):

1,2,3-Trihydroxybenzene, 2,3-Dihydroxyphenol, Pyrogallic acid

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25 G

€ 60,60

100 G

€ 132,00

250 G

€ 267,00

500 G

€ 533,00

€ 60,60


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About This Item

Linear Formula:
C6H3(OH)3
CAS Number:
Molecular Weight:
126.11
UNSPSC Code:
12191503
NACRES:
NA.21
PubChem Substance ID:
EC Number:
201-762-9
Beilstein/REAXYS Number:
907431
MDL number:
Grade:
HPLC grade
Assay:
≥98% (HPLC)
Technique(s):
HPLC: suitable
Application(s):
cell analysis
Bp:
309 °C (lit.)
Vapor pressure:
10 mmHg ( 167.7 °C)

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Product Name

Pyrogallol, ≥98% (HPLC)

InChI key

WQGWDDDVZFFDIG-UHFFFAOYSA-N

InChI

1S/C6H6O3/c7-4-2-1-3-5(8)6(4)9/h1-3,7-9H

SMILES string

Oc1cccc(O)c1O

grade

HPLC grade

vapor density

4.4 (vs air)

vapor pressure

10 mmHg ( 167.7 °C)

assay

≥98% (HPLC)

form

powder

technique(s)

HPLC: suitable

pH

5.8 (10 g/L)

bp

309 °C (lit.)

mp

133-134 °C (lit.)

solubility

ethanol: 50 mg/mL, clear, colorless

application(s)

cell analysis

Quality Level

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1 of 4

This Item
06931PHL89772254002
assay

≥98% (HPLC)

assay

≥98.0% (HPLC)

assay

≥98.0% (HPLC)

assay

-

Quality Level

100

Quality Level

100

Quality Level

-

Quality Level

200

application(s)

cell analysis

application(s)

cleaning products
cosmetics
food and beverages
personal care

application(s)

food and beverages

application(s)

-

solubility

ethanol: 50 mg/mL, clear, colorless

solubility

-

solubility

-

solubility

-

form

powder

form

-

form

-

form

solid

vapor density

4.4 (vs air)

vapor density

4.4 (vs air)

vapor density

4.4 (vs air)

vapor density

4.4 (vs air)

General description

Pyrogallol is a polyphenol[1] and allelochemical, found on Microcystis aeruginosa[2] and Emblica officinalis.[3]

Biochem/physiol Actions

Pyrogallol induces superoxide anion (O2-) generation[4] and in the presence of metal ions, it stimulates oxidative damage to DNA and lipids.[5]

Analysis Note

May contain black specks.

Application

Pyrogallol has been used:
  • in the superoxide dismutase (SOD) assay[4]
  • to induce modification in mitochondrial DNA and to characterize the same[5]
  • as a standard to confirm the presence of pyrogallol in butanol fraction of white rose petal extract[6]

pictograms

Health hazardExclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Muta. 2

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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Certificates of Analysis (COA)

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Effect of oxaliplatin combined with polyenephosphatidylcholine on the proliferation of human gastric cancer SGC-7901 cells
Jiang T, et al.
Oncology Letters, 12(6), 4538-4546 (2016)
Mitochondrial DNA acquires immunogenicity on exposure to nitrosative stress in patients with vitiligo
Al-Shobaili HA and Rasheed Z
Human immunology, 75(10), 1053-1061 (2014)
Neuroprotective effects of a butanol fraction of Rosa hybrida petals in a middle cerebral artery occlusion model
Yang G, et al.
Biomolecules & Therapeutics, 21(6), 454-454 (2013)
Allelopathic mechanism of pyrogallol to Microcystis aeruginosa PCC7806 (Cyanobacteria): from views of gene expression and antioxidant system
Shao J, et al.
Chemosphere, 75(7), 924-928 (2009)
Caspase inhibitor decreases apoptosis in pyrogallol-treated lung cancer Calu-6 cells via the prevention of GSH depletion
Han YH, et al.
International Journal of Oncology, 33(5), 1099-1105 (2008)

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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